Literature DB >> 29200134

Medical Monitoring for Occupational Asthma Among Toluene Diisocyanate Production Workers in the United States.

Laura D Cassidy1, Brent Doney, Mei Lin Wang, Laura Kurth, Patrick R Conner, James J Collins, Michael Carson, Don Molenaar, Carrie A Redlich, Eileen Storey.   

Abstract

OBJECTIVE: The aim of this study was to describe a study of medical monitoring methods and lessons learned in detecting health outcomes in U.S. plants producing toluene diisocyanate (TDI).
METHODS: A multidisciplinary team implemented a medical and environmental monitoring program in three TDI plants.
RESULTS: Of 269 eligible workers, 197 (73%) participated and 42 (21%) met symptom and/or lung function criteria that would trigger evaluation for possible asthma over 5 years of data collection. Subsequent evaluation was delayed for most, and a web-based data collection system improved timeliness.
CONCLUSION: Medical monitoring of TDI workers identified workers triggering further assessment per study protocol. Systems and/or personnel to ensure rapid follow-up are needed to highlight when triggering events represent potential cases of asthma needing further evaluation. Implementation of a research protocol requires resources and oversight beyond an occupational health program.

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Year:  2017        PMID: 29200134      PMCID: PMC5728423          DOI: 10.1097/JOM.0000000000001197

Source DB:  PubMed          Journal:  J Occup Environ Med        ISSN: 1076-2752            Impact factor:   2.162


  22 in total

1.  Asthmatic syndrome following exposure to tolylene diisocyanate.

Authors:  J W WOODBURY
Journal:  Ind Med Surg       Date:  1956-11

2.  Medical surveillance programme for diisocyanate exposure.

Authors:  Manon Labrecque; Jean-Luc Malo; Khadija M Alaoui; Khalil Rabhi
Journal:  Occup Environ Med       Date:  2010-10-15       Impact factor: 4.402

3.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

4.  [Clinical and experimental study of some cases of poisoning by desmodur T (1-2-4 and 1-2-6 di-isocyanates of toluene)].

Authors:  S FUCHS; P VALADE
Journal:  Arch Mal Prof       Date:  1951

Review 5.  Evidence based guidelines for the prevention, identification, and management of occupational asthma.

Authors:  P J Nicholson; P Cullinan; A J Newman Taylor; P S Burge; C Boyle
Journal:  Occup Environ Med       Date:  2005-05       Impact factor: 4.402

Review 6.  Respiratory effects of toluene diisocyanate in the workplace: a discussion of exposure-response relationships.

Authors:  M Gerald Ott; W F Diller; Athena T Jolly
Journal:  Crit Rev Toxicol       Date:  2003       Impact factor: 5.635

Review 7.  Current diagnostic methods for diisocyanate induced occupational asthma.

Authors:  D I Bernstein; A Jolly
Journal:  Am J Ind Med       Date:  1999-10       Impact factor: 2.214

8.  Reported incidence of occupational asthma in the United Kingdom, 1989-97.

Authors:  J C McDonald; H L Keynes; S K Meredith
Journal:  Occup Environ Med       Date:  2000-12       Impact factor: 4.402

Review 9.  Skin exposure to isocyanates: reasons for concern.

Authors:  Dhimiter Bello; Christina A Herrick; Thomas J Smith; Susan R Woskie; Robert P Streicher; Mark R Cullen; Youcheng Liu; Carrie A Redlich
Journal:  Environ Health Perspect       Date:  2006-11-28       Impact factor: 9.031

10.  Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry.

Authors:  James J Collins; Steve Anteau; Patrick R Conner; Laura D Cassidy; Brent Doney; Mei Lin Wang; Laura Kurth; Michael Carson; Don Molenaar; Carrie A Redlich; Eileen Storey
Journal:  J Occup Environ Med       Date:  2017-12       Impact factor: 2.162

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  3 in total

1.  Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry.

Authors:  James J Collins; Steve Anteau; Patrick R Conner; Laura D Cassidy; Brent Doney; Mei Lin Wang; Laura Kurth; Michael Carson; Don Molenaar; Carrie A Redlich; Eileen Storey
Journal:  J Occup Environ Med       Date:  2017-12       Impact factor: 2.162

2.  Serum Periostin Levels: A Potential Serologic Marker for Toluene Diisocyanate-Induced Occupational Asthma.

Authors:  Ji Ho Lee; Sang Ha Kim; Youngwoo Choi; Hoang Kim Tu Trinh; Eun Mi Yang; Ga Young Ban; Yoo Seob Shin; Young Min Ye; Kenji Izuhara; Hae Sim Park
Journal:  Yonsei Med J       Date:  2018-12       Impact factor: 2.759

3.  Risk Assessment for Toluene Diisocyanate and Respiratory Disease Human Studies.

Authors:  Robert M Park
Journal:  Saf Health Work       Date:  2020-12-13
  3 in total

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