Eoi Jong Seo1, June-Gone Kim. 1. Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Abstract
PURPOSE: To describe the retinal peripheral vascular morphology and to elucidate its relationship to microvascular abnormalities in normal fundus using ultra-widefield fluorescein angiography. METHODS: A total of 242 eyes from 167 consecutive patients were categorized into 3 groups: bilateral normal (n = 64), normal with contralateral eye affected with vascular disease (n = 82), and early diabetic eyes (n = 96). Peripheral vascular morphology was described and classified according to the shape. Microvascular abnormalities such as capillary telangiectasia, microaneurysm, or vascular leakage were documented, and the relationship between those abnormalities in each groups were analyzed. RESULTS: There were two distinctive peripheral vascular morphologies-loop and branching patterns. Microvascular abnormalities were more frequently found as loop patterns; this difference was most prominent when both eyes were normal. In case of normal eyes with contralateral eye affected with vascular disease or diabetic eyes, branching pattern microvascular abnormalities were relatively increased, whereas loop pattern still showed a large degree of microvascular abnormalities. CONCLUSION: In normal retinal periphery, we observed microvascular abnormalities and their relationship with vascular morphology, which could be influenced by the condition of the contralateral eye or systemic disease such as diabetes mellitus.
PURPOSE: To describe the retinal peripheral vascular morphology and to elucidate its relationship to microvascular abnormalities in normal fundus using ultra-widefield fluorescein angiography. METHODS: A total of 242 eyes from 167 consecutive patients were categorized into 3 groups: bilateral normal (n = 64), normal with contralateral eye affected with vascular disease (n = 82), and early diabetic eyes (n = 96). Peripheral vascular morphology was described and classified according to the shape. Microvascular abnormalities such as capillary telangiectasia, microaneurysm, or vascular leakage were documented, and the relationship between those abnormalities in each groups were analyzed. RESULTS: There were two distinctive peripheral vascular morphologies-loop and branching patterns. Microvascular abnormalities were more frequently found as loop patterns; this difference was most prominent when both eyes were normal. In case of normal eyes with contralateral eye affected with vascular disease or diabetic eyes, branching pattern microvascular abnormalities were relatively increased, whereas loop pattern still showed a large degree of microvascular abnormalities. CONCLUSION: In normal retinal periphery, we observed microvascular abnormalities and their relationship with vascular morphology, which could be influenced by the condition of the contralateral eye or systemic disease such as diabetes mellitus.
Authors: Karen W Jeng-Miller; Taha Soomro; Nathan L Scott; Prethy Rao; Elizabeth Marlow; Emmanuel Y Chang; Anna Ells; Felix Chau; Eric Nudleman; Charles M Calvo; Nish Patel; Roy Schwartz; Linda A Cernichiaro-Espinosa; Alexandrea Gabrielle Montoya; Jessica Goldstein; C Armitage Harper; Caroline R Baumal; Mary Elizabeth Hartnett; J William Harbour; Cagri G Besirli; Mrinali P Gupta; R V Paul Chan; Kimberly A Drenser; Antonio Capone; Timothy G Murray; Shizuo Mukai; Michael T Trese; Audina M Berrocal; Sui Chien Wong; Yoshihiro Yonekawa Journal: Ophthalmic Surg Lasers Imaging Retina Date: 2019-04-01 Impact factor: 1.300
Authors: Jin Young Kim; Mi Young Choi; Eoi Jong Seo; Seungheon Lee; Ji Soo Kim; Ju Byung Chae; Dong Yoon Kim; June-Gone Kim Journal: Sci Rep Date: 2020-08-12 Impact factor: 4.379