Literature DB >> 29199743

Sensing the impact of environment on small molecule differentiation of RNA sequences.

Christopher S Eubanks1, Amanda E Hargrove.   

Abstract

Using pattern recognition of RNA with small molecules (PRRSM) with fluorescent RNA chemosensors and aminoglycosides, we reveal the impact of changing environmental conditions on the differentiation of a range of RNA structures as well as the ability to predict different sequence/size compositions of five canonical RNA motifs.

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Year:  2017        PMID： 29199743     DOI： 10.1039/c7cc07157d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

Review 1.  RNA Structural Differentiation: Opportunities with Pattern Recognition.

Authors:  Christopher S Eubanks; Amanda E Hargrove
Journal:  Biochemistry       Date:  2018-12-18       Impact factor: 3.162

2.  Differentiation and classification of RNA motifs using small molecule-based pattern recognition.

Authors:  Giacomo Padroni; Christopher S Eubanks; Amanda E Hargrove
Journal:  Methods Enzymol       Date:  2019-06-13       Impact factor: 1.600

Review 3.  Understanding the Contributions of Conformational Changes, Thermodynamics, and Kinetics of RNA-Small Molecule Interactions.

Authors:  Aline Umuhire Juru; Neeraj N Patwardhan; Amanda E Hargrove
Journal:  ACS Chem Biol       Date:  2019-05-01       Impact factor: 5.100

4.  Small molecule-RNA targeting: starting with the fundamentals.

Authors:  Amanda E Hargrove
Journal:  Chem Commun (Camb)       Date:  2020-11-26       Impact factor: 6.222

5.  Visualizing RNA Conformational Changes via Pattern Recognition of RNA by Small Molecules.

Authors:  Christopher S Eubanks; Bo Zhao; Neeraj N Patwardhan; Rhese D Thompson; Qi Zhang; Amanda E Hargrove
Journal:  J Am Chem Soc       Date:  2019-03-26       Impact factor: 15.419

6.  R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures.

Authors:  Anita Donlic; Emily G Swanson; Liang-Yuan Chiu; Sarah L Wicks; Aline Umuhire Juru; Zhengguo Cai; Kamillah Kassam; Chris Laudeman; Bilva G Sanaba; Andrew Sugarman; Eunseong Han; Blanton S Tolbert; Amanda E Hargrove
Journal:  ACS Chem Biol       Date:  2022-05-20       Impact factor: 4.634

Review 7.  Targeting RNA in mammalian systems with small molecules.

Authors:  Anita Donlic; Amanda E Hargrove
Journal:  Wiley Interdiscip Rev RNA       Date:  2018-05-03       Impact factor: 9.957

8.  Probing the competition between duplex and G-quadruplex/i-motif structures using a conformation-sensitive fluorescent nucleoside probe.

Authors:  Pramod M Sabale; Arun A Tanpure; Seergazhi G Srivatsan
Journal:  Org Biomol Chem       Date:  2018-06-06       Impact factor: 3.876
  8 in total

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