Masao Yoshinaga1, Mari Iwamoto2, Hitoshi Horigome3, Naokata Sumitomo4, Hiroya Ushinohama5, Naomi Izumida6, Nobuo Tauchi7, Tatsuya Yoneyama8, Katsumi Abe9, Masami Nagashima7. 1. Department of Pediatrics, National Hospital Organization Kagoshima Medical Center. 2. Child Center, Saiseikai Yokohamashi Tobu Hospital. 3. Department of Child Health, Graduate School of Comprehensive Human Sciences, University of Tsukuba. 4. Department of Pediatric Cardiology, Saitama Medical University International Medical Center. 5. Pediatric Cardiology, Ohori Children's Clinic. 6. Pediatric Cardiology, Akebonocho Clinic. 7. Aichi Saiseikai Rehabilitation Hospital. 8. Fukuda Denshi Co., Ltd. 9. Tokyo Health Service Association.
Abstract
BACKGROUND: Reference values and the characteristics of the electrocardiographic (ECG) findings using a large number of subjects are lacking for children and adolescents.Methods and Results: A total of 56,753 digitally stored ECGs of participants in a school-based ECG screening system were obtained between 2006 and 2009 in Kagoshima, Japan. Each ECG was manually reviewed by 2 pediatric cardiologists and only ECGs with sinus rhythm were included. A final total of 48,401 ECGs from 16,773 1st (6 years old, 50% girls), 18,126 7th (12 years old, 51% girls), and 13,502 10th graders (15 years old, 52% girls) were selected. ECG variables showed differences in age and sex. However, the effects of age and sex on ECG variables such as the PQ interval, QRS voltage, and STJ segment were also different. The 98th percentile values of well-known surrogate parameters for ventricular hypertrophy in the present study were much higher than the conventional criteria. CONCLUSIONS: The present study of a large number of pediatric subjects showed that the effects of age and sex on ECG parameters are different, and that criteria for ventricular hypertrophy should be newly determined by age and sex. We have developed reference data for STJ segment elevation for children and adolescents. These findings are useful for creating guidelines and recommendations for interpretation of pediatric ECG.
BACKGROUND: Reference values and the characteristics of the electrocardiographic (ECG) findings using a large number of subjects are lacking for children and adolescents.Methods and Results: A total of 56,753 digitally stored ECGs of participants in a school-based ECG screening system were obtained between 2006 and 2009 in Kagoshima, Japan. Each ECG was manually reviewed by 2 pediatric cardiologists and only ECGs with sinus rhythm were included. A final total of 48,401 ECGs from 16,773 1st (6 years old, 50% girls), 18,126 7th (12 years old, 51% girls), and 13,502 10th graders (15 years old, 52% girls) were selected. ECG variables showed differences in age and sex. However, the effects of age and sex on ECG variables such as the PQ interval, QRS voltage, and STJ segment were also different. The 98th percentile values of well-known surrogate parameters for ventricular hypertrophy in the present study were much higher than the conventional criteria. CONCLUSIONS: The present study of a large number of pediatric subjects showed that the effects of age and sex on ECG parameters are different, and that criteria for ventricular hypertrophy should be newly determined by age and sex. We have developed reference data for STJ segment elevation for children and adolescents. These findings are useful for creating guidelines and recommendations for interpretation of pediatric ECG.
Entities:
Keywords:
Electrocardiography; Pediatrics; Reference values; Screening; Sudden cardiac death
Authors: Gabriel Cismaru; Cecilia Lazea; Lucian Mureşan; Gabriel Gusetu; Radu Rosu; Dana Pop; Dumitru Zdrenghea; Anca Daniela Farcaş; Simona Sorana Căinap Journal: Dis Markers Date: 2021-03-06 Impact factor: 3.434