Literature DB >> 29198631

Elective David I Procedure Has Excellent Long-Term Results: 20-Year Single-Center Experience.

Malakh L Shrestha1, Erik Beckmann2, Firas Abd Alhadi2, Heike Krueger2, Fiona Meyer-Bockenkamp2, Sebastian Bertele2, Nurbol Koigeldiyev2, Tim Kaufeld2, Felix Fleissner2, Wilhelm Korte2, Jan Schmitto2, Serghei Cebotari2, Wolfgang Harringer2, Axel Haverich2, Andreas Martens2.   

Abstract

BACKGROUND: We present our results after elective, isolated David I procedures over the past 20 years.
METHODS: Between 1993 and 2015, 197 patients (mean age 46 ± 17 years, 73% men) underwent isolated aortic valve reimplantation using straight tube grafts (David I procedure). Sixty patients (31%) had Marfan syndrome, and 24 (12%) had a bicuspid aortic valve. Twenty-four patients (12%) were operated through upper mini-sternotomy.
RESULTS: There were no perioperative deaths. Stroke rate was 1% (2 of 197). Discharge echocardiography showed none to trivial aortic regurgitation (AR) in 71% (139 of 197 patients) and mild AR in 26% (51 of 197 patients). Thirty-two patients (16%) died during follow-up (9.0 ± 5.5 years after operation). One death was aortic valve related. Twenty-six patients (13%) underwent aortic valve reoperations during follow-up (5.5 ± 5.0 years after operation). Late endocarditis occurred in 2 patients (1.0%). More than trivial AR at discharge predicted a higher reoperation rate. In 144 non-reoperated survivors, echocardiography showed none to trivial AR in 56 (39%), mild AR in 53 (37%), moderate AR in 19 (6.3%), and severe AR in 4 (2.7%) of the patients after 12 ± 5.3 years.
CONCLUSIONS: The valve-sparing David I procedure has excellent short- and long-term results. Erosion due to supposed leaflet contact with the straight tube graft was not observed in any patient, proving that using a straight graft has no negative impact on the leaflets. The "spared valve" (being native living tissue) seems to be more resistant to infection than prosthetic valves.
Copyright © 2018 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 29198631     DOI: 10.1016/j.athoracsur.2017.08.040

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  7 in total

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