Literature DB >> 29198331

Biomarkers in prostate cancer - Current clinical utility and future perspectives.

Alexander Kretschmer1, Derya Tilki2.   

Abstract

Current tendencies in the treatment course of prostate cancer patients increase the need for reliable biomarkers that help in decision-making in a challenging clinical setting. Within the last decade, several novel biomarkers have been introduced. In the following comprehensive review article, we focus on diagnostic (PHI®, 4K score, SelectMDx®, ConfirmMDx®, PCA3, MiPS, ExoDX®, mpMRI) and prognostic (OncotypeDX GPS®, Prolaris®, ProMark®, DNA-ploidy, Decipher®) biomarkers that are in widespread clinical use and are supported by evidence. Hereby, we focus on multiple clinical situations in which innovative biomarkers may guide decision-making in prostate cancer therapy. In addition, we describe novel liquid biopsy approaches (circulating tumor cells, cell-free DNA) that have been described as predictive biomarkers in metastatic castration-resistant prostate cancer and might support an individual patient-centred oncological approach in the nearer future.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Biomarker; Genetic marker; Molecular marker; Predictive; Prognostic; Prostate cancer

Mesh：

Substances：

Year:  2017        PMID： 29198331     DOI： 10.1016/j.critrevonc.2017.11.007

Source DB:  PubMed          Journal:  Crit Rev Oncol Hematol        ISSN： 1040-8428            Impact factor:   6.312


  41 in total

1.  Immunohistochemical Evaluation of PARP and Caspase-3 as Prognostic Markers in Prostate Carcinomas.

Authors:  Vitoria Acar; Fabio Leite Couto Fernandez; Fabio Fabian Buscariolo; Adriana Alonso Novais; Roseli Aparecida Matheus Pereira; Debora Aparecida Pires de Campos Zuccari
Journal:  Clin Med Res       Date:  2021-12

2.  Clinical Efficacy and Psychological Impact of Omaha-Based Continuing Care for Prostate Cancer Patients.

Authors:  Lanfang Luo; Fangfang Wang; Ling Wang; Jing Zhang; Xiaoyu Liu; Weifen Wang
Journal:  Comput Math Methods Med       Date:  2022-07-05       Impact factor: 2.809

3.  Characteristics of α2,3-sialyl N-glycosylated PSA as a biomarker for clinically significant prostate cancer in men with elevated PSA level.

Authors:  Tohru Yoneyama; Hayato Yamamoto; Mihoko Sutoh Yoneyama; Yuki Tobisawa; Shingo Hatakeyama; Takuma Narita; Hirotake Kodama; Masaki Momota; Hiroyuki Ito; Shintaro Narita; Fumiyasu Tsushima; Koji Mitsuzuka; Takahiro Yoneyama; Yasuhiro Hashimoto; Wilhelmina Duivenvoorden; Jehonathan H Pinthus; Shingo Kakeda; Akihiro Ito; Norihiko Tsuchiya; Tomonori Habuchi; Chikara Ohyama
Journal:  Prostate       Date:  2021-09-21       Impact factor: 4.012

Review 4.  Exosomes in Prostate Cancer Diagnosis, Prognosis and Therapy.

Authors:  Tomasz Lorenc; Katarzyna Klimczyk; Izabela Michalczewska; Monika Słomka; Grażyna Kubiak-Tomaszewska; Wioletta Olejarz
Journal:  Int J Mol Sci       Date:  2020-03-19       Impact factor: 5.923

Review 5.  Active surveillance for prostate and thyroid cancers: evolution in clinical paradigms and lessons learned.

Authors:  Lisa M Lowenstein; Spyridon P Basourakos; Michelle D Williams; Patricia Troncoso; Justin R Gregg; Timothy C Thompson; Jeri Kim
Journal:  Nat Rev Clin Oncol       Date:  2019-03       Impact factor: 66.675

6.  Transmembrane and Tetratricopeptide Repeat Containing 4 Is a Novel Diagnostic Marker for Prostate Cancer with High Specificity and Sensitivity.

Authors:  Rania Makboul; Islam F Abdelkawi; Dalia M Badary; Mahmoud R A Hussein; Johng S Rhim; Eman A Toraih; Mourad Zerfaoui; Zakaria Y Abd Elmageed
Journal:  Cells       Date:  2021-04-27       Impact factor: 6.600

7.  A panel of DNA methylation markers for the detection of prostate cancer from FV and DRE urine DNA.

Authors:  Igor Brikun; Deborah Nusskern; Andrew Decatus; Eric Harvey; Lin Li; Diha Freije
Journal:  Clin Epigenetics       Date:  2018-07-03       Impact factor: 6.551

8.  A Gleason score-related outcome model for human prostate cancer: a comprehensive study based on weighted gene co-expression network analysis.

Authors:  Yongzhi Wang; Zhonghua Yang
Journal:  Cancer Cell Int       Date:  2020-05-11       Impact factor: 5.722

Review 9.  Radiation Therapy After Radical Prostatectomy: What Has Changed Over Time?

Authors:  Fabio Zattoni; Isabel Heidegger; Veeru Kasivisvanathan; Alexander Kretschmer; Giancarlo Marra; Alessandro Magli; Felix Preisser; Derya Tilki; Igor Tsaur; Massimo Valerio; Roderick van den Bergh; Claudia Kesch; Francesco Ceci; Christian Fankhauser; Giorgio Gandaglia
Journal:  Front Surg       Date:  2021-07-09

10.  Expression of Androgen Receptor Variant 7 (AR-V7) in Circulated Tumor Cells and Correlation with Drug Resistance of Prostate Cancer Cells.

Authors:  Shuaibin Wang; Sen Yang; Cunjin Nan; Yijun Wang; Youhua He; Haiqi Mu
Journal:  Med Sci Monit       Date:  2018-10-04
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