Literature DB >> 29198066

Agelamasines A and B, diterpene alkaloids from an Okinawan marine sponge Agelas sp.

Sanghoon Lee1, Naonobu Tanaka2,3, Jun'ichi Kobayashi4, Yoshiki Kashiwada5.   

Abstract

Two new diterpene alkaloids having an N-methyladenine moiety, agelamasines A (1) and B (2), were isolated from an Okinawan marine sponge Agelas sp. The structures of 1 and 2 were elucidated on the basis of spectroscopic analyses. Agelamasine A (1) is the first diterpene alkaloid with a rearranged (4 → 2)-abeo-clerodane skeleton from a marine source, while agelamasine B (2) is a clerodane diterpene alkaloid.

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Keywords:  Agelamasines A and B; Agelas sp.; Diterpene alkaloid; Marine sponge; Rearranged clerodane

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Year:  2017        PMID: 29198066     DOI: 10.1007/s11418-017-1157-7

Source DB:  PubMed          Journal:  J Nat Med        ISSN: 1340-3443            Impact factor:   2.343


  2 in total

Review 1.  Secondary metabolites from marine sponges of the genus Agelas: a comprehensive update insight on structural diversity and bioactivity.

Authors:  Mei-Jun Chu; Meng Li; He Ma; Ping-Lin Li; Guo-Qiang Li
Journal:  RSC Adv       Date:  2022-03-09       Impact factor: 3.361

2.  Agesasines A and B, Bromopyrrole Alkaloids from Marine Sponges Agelas spp.

Authors:  Sanghoon Lee; Naonobu Tanaka; Sakura Takahashi; Daisuke Tsuji; Sang-Yong Kim; Mareshige Kojoma; Kohji Itoh; Jun'ichi Kobayashi; Yoshiki Kashiwada
Journal:  Mar Drugs       Date:  2020-08-30       Impact factor: 5.118

  2 in total

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