| Literature DB >> 29197009 |
Tejasvy Chollangi1,2, Hélène Clabault3,4,5, Andrée-Anne Hudon Thibeault3,4,5, Hannah E J Yong6,7,8, Shagun Narula9, Ellen Menkhorst10, J Thomas Sanderson3, Cathy Vaillancourt11,12,13, Padma Murthi14,15,16.
Abstract
In vitro functional analyses of cells are widely used to investigate the molecular mechanisms involved in preeclampsia. Common cellular functions studied include adhesion, apoptosis, proliferation, migration, and invasion. At present, most researchers will use endpoint experimental assays that only allow the determination of cell function at a single time point, with the need to repeat the experiment for an alternate time point. Here, we describe an electrical impedance-based tool that allows real-time monitoring of cells, which enables the efficient assessment of multiple time points over the duration of a single experiment.Keywords: Adhesion; Apoptosis; Functional assays; Invasion; Migration; Proliferation; xCELLigence® RTCA systems
Mesh：
Year: 2018 PMID： 29197009 DOI： 10.1007/978-1-4939-7498-6_20
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745