Literature DB >> 29196311

Unusual cause of encephalopathy after brain surgery.

Zayan Mahmooth1, James G Malcolm2, Jeremy S Wetzel2, Faiz U Ahmad2.   

Abstract

For patients who have had a recent neurosurgical procedure, a visit to the emergency department for encephalopathy may automatically prompt a neurosurgical consult. We present a case of a patient with a history of Chiari malformation decompressed 6 months prior who presented with a 2-week history of slowly progressive altered mental status, headache and imbalance-symptoms consistent with her initial Chiari symptoms, so neurosurgery was consulted. Imaging showed no acute abnormality, but laboratory results revealed metabolic acidosis with high salicylate levels. When reporting medication use, this patient initially left out that she had been taking Goody's powder (845 mg aspirin) for headaches, and long-term use led to metabolic encephalopathy. Despite a recent history of surgery, it is important to keep the differential diagnosis broad especially when there are signs of metabolic derangement. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  Headache (including Migraines); neurosurgery; toxicology

Mesh:

Substances:

Year:  2017        PMID: 29196311      PMCID: PMC5720312          DOI: 10.1136/bcr-2017-222253

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

Review 1.  History, anatomic forms, and pathogenesis of Chiari I malformations.

Authors:  Edgardo Schijman
Journal:  Childs Nerv Syst       Date:  2004-02-05       Impact factor: 1.475

2.  Normal anion gap salicylate poisoning.

Authors:  Dallas Wright; Jessica Sop
Journal:  Am J Emerg Med       Date:  2015-03-18       Impact factor: 2.469

3.  Acute cerebral white matter damage in lethal salicylate intoxication.

Authors:  Helmut Rauschka; Fahmy Aboul-Enein; Jan Bauer; Hans Nobis; Hans Lassmann; Manfred Schmidbauer
Journal:  Neurotoxicology       Date:  2006-07-13       Impact factor: 4.294

Review 4.  Extracorporeal Treatment for Salicylate Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup.

Authors:  David N Juurlink; Sophie Gosselin; Jan T Kielstein; Marc Ghannoum; Valéry Lavergne; Thomas D Nolin; Robert S Hoffman
Journal:  Ann Emerg Med       Date:  2015-05-15       Impact factor: 5.721

Review 5.  Position Paper on urine alkalinization.

Authors:  A T Proudfoot; E P Krenzelok; J A Vale
Journal:  J Toxicol Clin Toxicol       Date:  2004

6.  Negative anion gap metabolic acidosis in salicylate overdose--a zebra!

Authors:  Viren Kaul; Syed Haider Imam; Harvir Singh Gambhir; Arindam Sangha; Sravanthi Nandavaram
Journal:  Am J Emerg Med       Date:  2013-07-16       Impact factor: 2.469

Review 7.  Salicylate intoxication: a clinical review.

Authors:  Brian L Pearlman; Rashi Gambhir
Journal:  Postgrad Med       Date:  2009-07       Impact factor: 3.840

8.  Toxicity of salicylates.

Authors:  A T Proudfoot
Journal:  Am J Med       Date:  1983-11-14       Impact factor: 4.965

9.  Acid-base disturbances in the salicylate-intoxicated adult.

Authors:  P A Gabow; R J Anderson; D E Potts; R W Schrier
Journal:  Arch Intern Med       Date:  1978-10
  9 in total

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