Literature DB >> 29195934

Photocrosslinker technology: An antimicrobial efficacy of cinnamaldehyde cross-linked low-density polyethylene (Cin-C-LDPE) as a novel food wrapper.

H M Manukumar1, S Umesha2.   

Abstract

In recent years much attention has been devoted to active packaging technologies that offer new opportunities for the food industry and food preservation. The spoilage of food products during post process handling leads to food contamination and causes life-threatening food-borne illness. The methicillin-resistant Staphylococcus aureus (MRSA) 090 is one of the food-borne pathogens associated with food poisoning that leads to an outbreak of perilous human infections worldwide. The development of resistance in bacteria and diffusion of coated synthetic preservatives into food are the major problem in food packaging industries. In the present work, we have developed a new food wrap method by cross-linking cinnamaldehyde on low-density polyethylene (Cin-C-LDPE) using novel photocrosslinker technology. The cinnamaldehyde showed potent antimicrobial activity (145mg/mL of MIC) against MRSA 090 and radical scavenging activity (RSA). The cinnamaldehyde was successfully cross-linked to LDPE and exhibited excellent antibiofilm properties against MRSA090 compared to bare LDPE. This positive interaction of developed Cin-C-LDPE against MRSA090 biofilm was confirmed by SEM and FT-IR studies, and results showed the damaged cell membrane architecture, inturn abridged adherence of MRSA090. The Cin-C-LDPE wrapped chicken, mutton, cheese, and grapes showed 2.5±0.15 log MRSA 090 reduction at the end of 10th day compared to the bare LDPE wrapped food samples. This clearly concludes that for the first time we have developed a novel Cin-C-LDPE food wrap technology effectively involved in biocidal activity against MRSA090. Applying this new strategy to develop food wrap containing nontoxic natural antimicrobial to target cell membrane components is the upcoming challenging and promising research gap remains in the food packaging industry for the future world.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Biocidal activity; Cin-C-LDPE; Cinnamaldehyde; Food wrap; Photocrosslinkig; S. aureus

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Year:  2017        PMID: 29195934     DOI: 10.1016/j.foodres.2017.09.095

Source DB:  PubMed          Journal:  Food Res Int        ISSN: 0963-9969            Impact factor:   6.475


  2 in total

1.  Novel T-C@AgNPs mediated biocidal mechanism against biofilm associated methicillin-resistant Staphylococcus aureus (Bap-MRSA) 090, cytotoxicity and its molecular docking studies.

Authors:  H M Manukumar; B Chandrasekhar; K P Rakesh; A P Ananda; M Nandhini; P Lalitha; S Sumathi; Hua-Li Qin; S Umesha
Journal:  Medchemcomm       Date:  2017-10-31       Impact factor: 3.597

Review 2.  Cinnamomum: The New Therapeutic Agents for Inhibition of Bacterial and Fungal Biofilm-Associated Infection.

Authors:  Mojtaba Didehdar; Zahra Chegini; Seidamir Pasha Tabaeian; Shabnam Razavi; Aref Shariati
Journal:  Front Cell Infect Microbiol       Date:  2022-07-08       Impact factor: 6.073

  2 in total

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