Literature DB >> 29195860

GDF15-From Biomarker to Allostatic Hormone.

Stephen O'Rahilly1.   

Abstract

With the identification of its receptor in a highly specific region of the brain, interesting issues come to light regarding the normal physiological functions of GDF15, a secreted protein long identified as a biomarker of diverse disease states.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 29195860     DOI: 10.1016/j.cmet.2017.10.017

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  20 in total

1.  GDF15 Induces an Aversive Visceral Malaise State that Drives Anorexia and Weight Loss.

Authors:  Tito Borner; Hallie S Wald; Misgana Y Ghidewon; Bei Zhang; Zhidan Wu; Bart C De Jonghe; Danna Breen; Harvey J Grill
Journal:  Cell Rep       Date:  2020-04-21       Impact factor: 9.423

2.  GDF15 Induces Anorexia through Nausea and Emesis.

Authors:  Tito Borner; Evan D Shaulson; Misgana Y Ghidewon; Amanda B Barnett; Charles C Horn; Robert P Doyle; Harvey J Grill; Matthew R Hayes; Bart C De Jonghe
Journal:  Cell Metab       Date:  2020-01-09       Impact factor: 27.287

Review 3.  Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus.

Authors:  Adilson Guilherme; Felipe Henriques; Alexander H Bedard; Michael P Czech
Journal:  Nat Rev Endocrinol       Date:  2019-04       Impact factor: 43.330

4.  Cutting Edge: CD36 Mediates Phagocyte Tropism and Avirulence of Toxoplasma gondii.

Authors:  Yanlin Zhao; Jojo Reyes; Eliezer Rovira-Diaz; Barbara A Fox; David J Bzik; George S Yap
Journal:  J Immunol       Date:  2021-08-16       Impact factor: 5.426

Review 5.  GDF15: A Hormone Conveying Somatic Distress to the Brain.

Authors:  Samuel M Lockhart; Vladimir Saudek; Stephen O'Rahilly
Journal:  Endocr Rev       Date:  2020-08-01       Impact factor: 19.871

6.  Serum FGF-21, GDF-15, and blood mtDNA copy number are not biomarkers of Parkinson disease.

Authors:  Ryan L Davis; Siew L Wong; Phillippa J Carling; Thomas Payne; Carolyn M Sue; Oliver Bandmann
Journal:  Neurol Clin Pract       Date:  2020-02

7.  Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.

Authors:  Irene Cimino; Hanna Kim; Y C Loraine Tung; Kent Pedersen; Debra Rimmington; John A Tadross; Sara N Kohnke; Ana Neves-Costa; André Barros; Stephanie Joaquim; Don Bennett; Audrey Melvin; Samuel M Lockhart; Anthony J Rostron; Jonathan Scott; Hui Liu; Keith Burling; Peter Barker; Menna R Clatworthy; E-Chiang Lee; A John Simpson; Giles S H Yeo; Luís F Moita; Kendra K Bence; Sebastian Beck Jørgensen; Anthony P Coll; Danna M Breen; Stephen O'Rahilly
Journal:  Proc Natl Acad Sci U S A       Date:  2021-07-06       Impact factor: 12.779

8.  Vomiting in pregnancy is associated with a higher risk of low birth weight: a cohort study.

Authors:  Clive J Petry; Ken K Ong; Kathryn Beardsall; Ieuan A Hughes; Carlo L Acerini; David B Dunger
Journal:  BMC Pregnancy Childbirth       Date:  2018-05-04       Impact factor: 3.007

9.  Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study.

Authors:  Clive J Petry; Ken K Ong; Keith A Burling; Peter Barker; Sandra F Goodburn; John R B Perry; Carlo L Acerini; Ieuan A Hughes; Rebecca C Painter; Gijs B Afink; David B Dunger; Stephen O'Rahilly
Journal:  Wellcome Open Res       Date:  2018-09-21

10.  Higher Pericyte Content and Secretory Activity of Microfragmented Human Adipose Tissue Compared to Enzymatically Derived Stromal Vascular Fraction.

Authors:  Bianca Vezzani; Isaac Shaw; Hanna Lesme; Li Yong; Nusrat Khan; Carlo Tremolada; Bruno Péault
Journal:  Stem Cells Transl Med       Date:  2018-09-26       Impact factor: 6.940

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