Charles P Hannon1, Alexander E Weber2, Matthew Gitelis2, Maximillian A Meyer2, Adam B Yanke2, Brian J Cole2. 1. Section of Cartilage Restoration and Sports Medicine, Department of Orthopaedics, Rush University Medical Center, Chicago, Illinois, U.S.A.. Electronic address: charles.p.hannon@gmail.com. 2. Section of Cartilage Restoration and Sports Medicine, Department of Orthopaedics, Rush University Medical Center, Chicago, Illinois, U.S.A.
Abstract
PURPOSE: To compare the osteochondral allograft (OCA) outcomes of bipolar defects with isolated femoral defects and to investigate the optimal treatment of bipolar defects by comparing femoral OCA with tibial debridement to femoral OCA and tibial microfracture. METHODS: A series of patients with 2-year follow-up from March 2004 to September 2015 after femoral OCA for bipolar chondral defects was identified. Group 1 contained patients with tibial defects treated with debridement and group 2 contained patients with microfractured tibial defects. A third group (group 3) with isolated femoral defects treated with OCA was identified and matched by gender, body mass index (BMI), laterality, and OCA size to groups 1 and 2. Patient-specific, defect-specific, intraoperative, and postoperative data including patient-reported outcomes were collected on all patients. The study groups were compared using analyses of variance, paired sample t tests, and χ-square analyses. RESULTS: Thirty-six patients who had femoral OCA for bipolar lesions were identified with 20 patients in group 1 and 16 patients in group 2. Group 3 had 20 patients. There were no differences between the 3 groups in terms of gender (P = .616), BMI (P = .271), number of previous surgeries (P = .451), femoral or tibial defect size (P = .296), and OCA size (P = .981). Preoperative to postoperative patient-reported clinical outcomes (PROs) revealed statistical and clinically meaningful improvement in all 3 groups, but did not differ between groups. Patient-specific and defect-specific factors did not correlate with PROs. The graft survivorship for group 1 was 85% at 4.5 years, 100% for group 2 at 2.5 years, and 95% for group 3 at 3.8 years. CONCLUSIONS: Regardless of tibial treatment, patients with bipolar defects treated with femoral OCA have clinically meaningful improvements in PROs and excellent graft survivorship comparable to isolated femoral OCAs at more than 2 years. LEVEL OF EVIDENCE: Level III, case-control study.
PURPOSE: To compare the osteochondral allograft (OCA) outcomes of bipolar defects with isolated femoral defects and to investigate the optimal treatment of bipolar defects by comparing femoral OCA with tibial debridement to femoral OCA and tibial microfracture. METHODS: A series of patients with 2-year follow-up from March 2004 to September 2015 after femoral OCA for bipolar chondral defects was identified. Group 1 contained patients with tibial defects treated with debridement and group 2 contained patients with microfractured tibial defects. A third group (group 3) with isolated femoral defects treated with OCA was identified and matched by gender, body mass index (BMI), laterality, and OCA size to groups 1 and 2. Patient-specific, defect-specific, intraoperative, and postoperative data including patient-reported outcomes were collected on all patients. The study groups were compared using analyses of variance, paired sample t tests, and χ-square analyses. RESULTS: Thirty-six patients who had femoral OCA for bipolar lesions were identified with 20 patients in group 1 and 16 patients in group 2. Group 3 had 20 patients. There were no differences between the 3 groups in terms of gender (P = .616), BMI (P = .271), number of previous surgeries (P = .451), femoral or tibial defect size (P = .296), and OCA size (P = .981). Preoperative to postoperative patient-reported clinical outcomes (PROs) revealed statistical and clinically meaningful improvement in all 3 groups, but did not differ between groups. Patient-specific and defect-specific factors did not correlate with PROs. The graft survivorship for group 1 was 85% at 4.5 years, 100% for group 2 at 2.5 years, and 95% for group 3 at 3.8 years. CONCLUSIONS: Regardless of tibial treatment, patients with bipolar defects treated with femoral OCA have clinically meaningful improvements in PROs and excellent graft survivorship comparable to isolated femoral OCAs at more than 2 years. LEVEL OF EVIDENCE: Level III, case-control study.
Authors: Anirudh K Gowd; Alexander E Weimer; Danielle E Rider; Edward C Beck; Avinesh Agarwalla; Lisa K O'Brien; Michael J Alaia; Cristin M Ferguson; Brian R Waterman Journal: Arthrosc Sports Med Rehabil Date: 2021-06-24
Authors: Heath P Melugin; Christopher D Bernard; Christopher L Camp; Michael J Stuart; Daniel B F Saris; Norimasa Nakamura; Aaron J Krych Journal: Cartilage Date: 2019-06-16 Impact factor: 3.117
Authors: Heath P Melugin; Christopher D Bernard; Christopher L Camp; Daniel B F Saris; Aaron J Krych Journal: Cartilage Date: 2019-06-16 Impact factor: 3.117
Authors: Michael Stark; Somnath Rao; Brendan Gleason; Robert A Jack; Bradford Tucker; Sommer Hammoud; Kevin B Freedman Journal: Orthop J Sports Med Date: 2021-07-27