L Storme 1 , J Boubnova 2 , S Mur 1 , L Pognon 1 , D Sharma 1 , E Aubry 1 , R Sfeir 1 , P Vaast 1 , T Rakza 1 , A Benachi 3 Show Affiliations »
Abstract
The French Rare Disease Reference Center for congenital diaphragmatic hernia (CDH) was created in 2008, to implement a national protocol for foetuses and children with this serious condition. Neonatal mortality from CDH is 30-40%, mainly due to pulmonary hypoplasia and persistent pulmonary hypertension, and half of those who live have high respiratory, nutritional and digestive morbidity. CDH management requires long-term and specialised multidisciplinary care. It has been well established that a standardised management protocol improves the prognosis of children with CDH. CONCLUSION: Organising health care and implementing a nationwide French protocol were key factors for reducing mortality and morbidity from CDH. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
The French Rare Disease Reference Center for congenital diaphragmatic hernia (CDH) was created in 2008, to implement a national protocol for foetuses and children with this serious condition. Neonatal mortality from CDH is 30-40%, mainly due to pulmonary hypoplasia and persistent pulmonary hypertension , and half of those who live have high respiratory, nutritional and digestive morbidity. CDH management requires long-term and specialised multidisciplinary care. It has been well established that a standardised management protocol improves the prognosis of children with CDH. CONCLUSION: Organising health care and implementing a nationwide French protocol were key factors for reducing mortality and morbidity from CDH. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
Entities: Disease
Species
Keywords:
Congenital diaphragmatic hernia; Mortality; National protocol; Persistent pulmonary hypertension; Pulmonary hypoplasia
Mesh： See more »
Year: 2018
PMID： 29193315 DOI： 10.1111/apa.14169
Source DB: PubMed Journal: Acta Paediatr ISSN： 0803-5253 Impact factor: 2.299