Literature DB >> 29192258

Alzheimer disease: CRISPR activation reveals hidden γ-secretase defect in fibroblasts from patients with familial AD.

Charlotte Ridler.   

Abstract

Entities:  

Year:  2017        PMID： 29192258     DOI： 10.1038/nrneurol.2017.172

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN： 1759-4758            Impact factor:   42.937


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  1 in total

1.  CRISPR Transcriptional Activation Analysis Unmasks an Occult γ-Secretase Processivity Defect in Familial Alzheimer's Disease Skin Fibroblasts.

Authors:  Keiichi Inoue; Luis M A Oliveira; Asa Abeliovich
Journal:  Cell Rep       Date:  2017-11-14       Impact factor: 9.423
  1 in total

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