Dai Zheng1, Zhu Mingyue2, Shi Wei3, Li Min4, Chen Wanhong5, Dai Qiliang4, Jiang Yongjun6, Liu Xinfeng7. 1. Department of Neurology, Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu Province, China. 2. Department of Intensive Care Unit, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China. 3. Department of Intensive Care Unit, The Affiliated Brain Hospital with Nanjing Medical University, Nanjing, Jiangsu Province. 4. Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China. 5. Department of Neurology, Xi'an XD Group Hospital, Xi'an, China. 6. Department of Neurology, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address: jiangyjnju@gmail.com. 7. Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China. Electronic address: xfliu2@vip.163.com.
Abstract
BACKGROUND AND OBJECTIVES: In-stent restenosis (ISR) remains a challenge for vertebrobasilar artery stenting (VBAS). We aimed to investigate the incidence and risk factors of ISR. METHODS: This was a retrospective study. From July 28, 2005, to July 30, 2015, patients who received VBAS with an angiographic follow-up time of 6 to 12 months after surgery were enrolled. The clinical and angiographic issues were recorded and analyzed. RESULTS: In total, 283 patients with 335 stents were incorporated into the study. Vertebral ostial lesions accounted for 73.4% (246/335) of the lesions. During the follow-up period, 58 patients with 60 stents experienced ISR (>50%). Stepwise logistic regression analysis showed that the degree of residual stenosis, stent diameter, and alcohol consumption were independent predictors of ISR. CONCLUSIONS: Our study demonstrated the incidence and risk factors of ISR after VBAS. This retrospective study with the largest cohort to date provided insight into the occurrence of ISR after VBAS.
BACKGROUND AND OBJECTIVES: In-stent restenosis (ISR) remains a challenge for vertebrobasilar artery stenting (VBAS). We aimed to investigate the incidence and risk factors of ISR. METHODS: This was a retrospective study. From July 28, 2005, to July 30, 2015, patients who received VBAS with an angiographic follow-up time of 6 to 12 months after surgery were enrolled. The clinical and angiographic issues were recorded and analyzed. RESULTS: In total, 283 patients with 335 stents were incorporated into the study. Vertebral ostial lesions accounted for 73.4% (246/335) of the lesions. During the follow-up period, 58 patients with 60 stents experienced ISR (>50%). Stepwise logistic regression analysis showed that the degree of residual stenosis, stent diameter, and alcohol consumption were independent predictors of ISR. CONCLUSIONS: Our study demonstrated the incidence and risk factors of ISR after VBAS. This retrospective study with the largest cohort to date provided insight into the occurrence of ISR after VBAS.