Eric J Schwaber1,2, Nia Fogelman3, Ethan K Sobol2, Devi Mehrotra2, Jonathan A Powell2, Umar Mian2, David C Gritz2,4. 1. a Tufts University School of Medicine , Boston , MA , USA. 2. b Department of Ophthalmology and Visual Science and Department of Epidemiology and Population Science , Montefiore Medical Center and the Albert Einstein College of Medicine , Bronx , NY. 3. c Department of Psychology , Stony Brook University , Stony Brook , NY , USA. 4. d Department of Ophthalmology , The Johns Hopkins Wilmer Eye Institute , Baltimore , MD , USA.
Abstract
PURPOSE: Retinal vascular occlusions can lead to sudden and permanent visual impairment or blindness. Few epidemiological studies on retinal vascular occlusions have been conducted, especially on diverse populations. METHODS: This is a retrospective case-control study of all incident retinal vascular occlusions occurring during a three and one-half year study period at Montefiore Medical Center, capturing all potential cases by diagnosis codes. Patients with retinal venous occlusions (RVO) and retinal arterial occlusions (RAO) were analyzed separately and compared to age-matched control groups. RESULTS: All potential charts (n = 700) were reviewed, confirming 214 RVO and 35 RAO incident cases. In multivariable analyses, RVO was associated with type 2 diabetes mellitus (OR 2.41, p < 0.001), history of cerebrovascular accident (OR 2.14, p = 0.011), hypertension (OR 1.83, p = 0.004), glaucoma (OR 6.91, p < 0.001), black race (OR 3.72, p < 0.001), and male gender (OR 2.19 p < 0.001). RAO was significantly associated with current and former smoking combined (OR 8.95, p = 0.021) and male gender (OR 2.56, p = 0.038). CONCLUSION: Cardiovascular risk factors and glaucoma are reaffirmed as significant predictors of retinal vascular occlusions in a diverse patient population. Retinal vascular occlusions are more common in certain races and ethnicities, and further study into this may help identify high-risk individuals based on demographics.
PURPOSE:Retinal vascular occlusions can lead to sudden and permanent visual impairment or blindness. Few epidemiological studies on retinal vascular occlusions have been conducted, especially on diverse populations. METHODS: This is a retrospective case-control study of all incident retinal vascular occlusions occurring during a three and one-half year study period at Montefiore Medical Center, capturing all potential cases by diagnosis codes. Patients with retinal venous occlusions (RVO) and retinal arterial occlusions (RAO) were analyzed separately and compared to age-matched control groups. RESULTS: All potential charts (n = 700) were reviewed, confirming 214 RVO and 35 RAO incident cases. In multivariable analyses, RVO was associated with type 2 diabetes mellitus (OR 2.41, p < 0.001), history of cerebrovascular accident (OR 2.14, p = 0.011), hypertension (OR 1.83, p = 0.004), glaucoma (OR 6.91, p < 0.001), black race (OR 3.72, p < 0.001), and male gender (OR 2.19 p < 0.001). RAO was significantly associated with current and former smoking combined (OR 8.95, p = 0.021) and male gender (OR 2.56, p = 0.038). CONCLUSION: Cardiovascular risk factors and glaucoma are reaffirmed as significant predictors of retinal vascular occlusions in a diverse patient population. Retinal vascular occlusions are more common in certain races and ethnicities, and further study into this may help identify high-risk individuals based on demographics.
Authors: Marie Ørskov; Henrik Vorum; Torben Bjerregaard Larsen; Gregory Y H Lip; Toke Bek; Flemming Skjøth Journal: Int Ophthalmol Date: 2022-09-02 Impact factor: 2.029
Authors: John J McDermott; Terrence C Lee; Alison X Chan; Gordon Y Ye; Bita Shahrvini; Bharanidharan Radha Saseendrakumar; Henry Ferreyra; Eric Nudleman; Sally L Baxter Journal: Ophthalmol Sci Date: 2021-12-20
Authors: Marie Ørskov; Henrik Vorum; Torben Bjerregaard Larsen; Gregory Y H Lip; Toke Bek; Flemming Skjøth Journal: Int Ophthalmol Date: 2022-03-19 Impact factor: 2.029
Authors: Yangjiani Li; Nathan E Hall; Suzann Pershing; Leslie Hyman; Julia A Haller; Aaron Y Lee; Cecilia S Lee; Michael Chiang; Flora Lum; Joan W Miller; Alice Lorch; Tobias Elze Journal: Ophthalmol Retina Date: 2021-05-12