BACKGROUND: Rotavirus vaccines created the opportunity to control diarrhea in children. We describe the rotavirus genotypes before and after the rotavirus vaccine introduction in Brazil. METHODS: We reviewed the distribution of rotavirus genotypes in Brazil before and after vaccine introduction by searching publication. RESULTS: Eighty-six studies reported 6884 (15.2%) rotavirus episodes among 45,305 children. Rotavirus caused 22.4% and 11.6% of cases before and after vaccine introduction. G1P[8], G9P[8] and G2P[4] heterotypic strains were most common before and after vaccine introduction. CONCLUSIONS: The vaccines may have selected heterotypic strains in this highly vaccinated population.
BACKGROUND: Rotavirus vaccines created the opportunity to control diarrhea in children. We describe the rotavirus genotypes before and after the rotavirus vaccine introduction in Brazil. METHODS: We reviewed the distribution of rotavirus genotypes in Brazil before and after vaccine introduction by searching publication. RESULTS: Eighty-six studies reported 6884 (15.2%) rotavirus episodes among 45,305 children. Rotavirus caused 22.4% and 11.6% of cases before and after vaccine introduction. G1P[8], G9P[8] and G2P[4] heterotypic strains were most common before and after vaccine introduction. CONCLUSIONS: The vaccines may have selected heterotypic strains in this highly vaccinated population.
Authors: Juliana T T Fritzen; Marcos V Oliveira; Elis Lorenzetti; Flávia M Miyabe; Mariana P Viziack; Carlos A Rodrigues; Henderson Ayres; Alice F Alfieri; Amauri A Alfieri Journal: Vet Microbiol Date: 2019-02-18 Impact factor: 3.293