| Literature DB >> 29189116 |
Peyman Bemani1, Mozafar Mohammadi2, Ali Hakakian3.
Abstract
The most common recombinant antibody format is the single chain fragment variable (scFv) which it contains the complete antigen-binding domains of an intact antibody. ScFv fragments have found vast medical and non-medical applications. Several approaches have been employed to increase the affinity, avidity and structural stability related to these antibody fragments. Most approaches related to scFv improvement have been included in this review. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: affinity; antibody fragments; avidity; recombinant antibody; scFv; scFv stability.
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Year: 2018 PMID： 29189116 DOI： 10.2174/0929866525666171129225436
Source DB: PubMed Journal: Protein Pept Lett ISSN： 0929-8665 Impact factor: 1.890