Literature DB >> 29187491

Incidence and Risk Factors of Symptomatic Hiatal Hernia Following Resection for Gastric and Esophageal Cancer.

Andreas Andreou1,2, Sina Pesthy3, Benjamin Struecker3,4, Mehran Dadras3, Jonas Raakow3, Sebastian Knitter3, Gregor Duwe3, Igor M Sauer3, Anika Sophie Beierle3, Christian Denecke3, Sascha Chopra3, Johann Pratschke3, Matthias Biebl3.   

Abstract

BACKGROUND/AIM: Symptomatic hiatal hernia (HH) following resection for gastric or esophageal cancer is a potentially life-threatening event that may lead to emergent surgery. However, the incidence and risk factors of this complication remain unclear. PATIENTS AND METHODS: Data of patients who underwent resection for gastric or esophageal cancer between 2005 and 2012 were assessed and the incidence of symptomatic HH was evaluated. Factors associated with an increased risk for HH were investigated.
RESULTS: Resection of gastric or esophageal cancer was performed in 471 patients. The primary tumor was located in the stomach, cardia and esophagus in 36%, 24%, and 40% of patients, respectively. The incidence of symptomatic HH was 2.8% (n=13). All patients underwent surgical hernia repair, 8 patients (61.5%) required emergent procedure, and 3 patients (23%) underwent bowel resection. Morbidity and mortality after HH repair was 38% and 8%, respectively. Factors associated with increased risk for symptomatic HH included Body-Mass-Index (median BMI with HH 27 (23-35) vs. BMI without HH 25 (15-51), p=0.043), diabetes (HH rate: with diabetes, 6.3% vs. without diabetes, 2%, p=0.034), tumor location (HH rate: stomach, 1.2% vs. esophagus, 1.1% vs. cardia, 7.9%, p=0.001), and resection type (HH rate: total/subtotal gastrectomy, 0.7% vs. transthoracic esophagectomy, 2.7% vs. extended gastrectomy, 6.1%, p=0.038).
CONCLUSION: HH is a major adverse event after resection for gastric or esophageal cancer especially among patients undergoing extended gastrectomy for cardia cancer requiring a high rate of repeat surgery. Therefore, intensive follow-up examinations for high-risk patients and early diagnosis of asymptomatic patients are essential for selecting patients for elective surgery to avoid unpredictable emergent events with high morbidity and mortality. Copyright
© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Hiatal hernia; esophageal cancer; gastric cancer

Mesh:

Year:  2017        PMID: 29187491     DOI: 10.21873/anticanres.12173

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  5 in total

1.  Hiatal Hernia with Acute Obstructive Symptoms After Minimally Invasive Oesophagectomy.

Authors:  Merel Lubbers; Ewout A Kouwenhoven; Justin K Smit; Marc J van Det
Journal:  J Gastrointest Surg       Date:  2020-07-24       Impact factor: 3.452

2.  Paraconduit hiatal hernia following minimally invasive oesophagectomy in an emergent setting.

Authors:  Thomas Zheng Jie Teng; Aung Myint Oo; Kon Voi Tay
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2022-05-13

3.  Identification of crucial miRNAs and genes in esophageal squamous cell carcinoma by miRNA-mRNA integrated analysis.

Authors:  Xiaowu Zhong; Guangcheng Huang; Qiang Ma; Hebin Liao; Chang Liu; Wenjie Pu; Lei Xu; Yan Cai; Xiaolan Guo
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

4.  Trans-hiatal herniation following esophagectomy or gastrectomy: retrospective single-center experiences with a potential surgical emergency.

Authors:  P U Oppelt; I Askevold; R Hörbelt; F C Roller; W Padberg; A Hecker; M Reichert
Journal:  Hernia       Date:  2021-03-13       Impact factor: 2.920

5.  Diaphragmatic herniation after esophagogastric surgery: systematic review and meta-analysis.

Authors:  Davide Bona; Francesca Lombardo; Kazuhide Matsushima; Marta Cavalli; Valerio Panizzo; Paolo Mendogni; Gianluca Bonitta; Giampiero Campanelli; Alberto Aiolfi
Journal:  Langenbecks Arch Surg       Date:  2021-06-15       Impact factor: 3.445

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.