Literature DB >> 29184180

RNA takes over control of DNA break repair.

Francesca Storici1, Ailone E Tichon1.   

Abstract

Small RNAs generated at DNA break sites are implicated in mammalian DNA repair. Now, a study shows that following the formation of DNA double-strand breaks, bidirectional transcription events adjacent to the break generate small RNAs that trigger the DNA damage response by local RNA:RNA interactions.

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Year:  2017        PMID： 29184180     DOI： 10.1038/ncb3645

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  13 in total

1.  DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination.

Authors:  Leizhen Wei; Satoshi Nakajima; Stefanie Böhm; Kara A Bernstein; Zhiyuan Shen; Michael Tsang; Arthur S Levine; Li Lan
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-22       Impact factor: 11.205

2.  Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair.

Authors:  Corina Ohle; Rafael Tesorero; Géza Schermann; Nikolay Dobrev; Irmgard Sinning; Tamás Fischer
Journal:  Cell       Date:  2016-10-27       Impact factor: 41.582

3.  A role for small RNAs in DNA double-strand break repair.

Authors:  Wei Wei; Zhaoqing Ba; Min Gao; Yang Wu; Yanting Ma; Simon Amiard; Charles I White; Jannie Michaela Rendtlew Danielsen; Yun-Gui Yang; Yijun Qi
Journal:  Cell       Date:  2012-03-22       Impact factor: 41.582

Review 4.  DNA double-strand breaks: signaling, repair and the cancer connection.

Authors:  K K Khanna; S P Jackson
Journal:  Nat Genet       Date:  2001-03       Impact factor: 38.330

5.  Requirement for Xist in X chromosome inactivation.

Authors:  G D Penny; G F Kay; S A Sheardown; S Rastan; N Brockdorff
Journal:  Nature       Date:  1996-01-11       Impact factor: 49.962

6.  Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre.

Authors:  Ezgi Hacisuleyman; Loyal A Goff; Cole Trapnell; Adam Williams; Jorge Henao-Mejia; Lei Sun; Patrick McClanahan; David G Hendrickson; Martin Sauvageau; David R Kelley; Michael Morse; Jesse Engreitz; Eric S Lander; Mitch Guttman; Harvey F Lodish; Richard Flavell; Arjun Raj; John L Rinn
Journal:  Nat Struct Mol Biol       Date:  2014-01-26       Impact factor: 15.369

7.  Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.

Authors:  Sungyul Lee; Florian Kopp; Tsung-Cheng Chang; Anupama Sataluri; Beibei Chen; Sushama Sivakumar; Hongtao Yu; Yang Xie; Joshua T Mendell
Journal:  Cell       Date:  2015-12-24       Impact factor: 41.582

8.  Site-specific DICER and DROSHA RNA products control the DNA-damage response.

Authors:  Sofia Francia; Flavia Michelini; Alka Saxena; Dave Tang; Michiel de Hoon; Viviana Anelli; Marina Mione; Piero Carninci; Fabrizio d'Adda di Fagagna
Journal:  Nature       Date:  2012-08-09       Impact factor: 49.962

9.  Transcript-RNA-templated DNA recombination and repair.

Authors:  Havva Keskin; Ying Shen; Fei Huang; Mikir Patel; Taehwan Yang; Katie Ashley; Alexander V Mazin; Francesca Storici
Journal:  Nature       Date:  2014-09-03       Impact factor: 49.962

10.  A small RNA response at DNA ends in Drosophila.

Authors:  Katharina M Michalik; Romy Böttcher; Klaus Förstemann
Journal:  Nucleic Acids Res       Date:  2012-07-30       Impact factor: 16.971
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  4 in total

1.  A diRNA-protein scaffold module mediates SMC5/6 recruitment in plant DNA repair.

Authors:  Jieming Jiang; Xiaolin Ou; Danlu Han; Zhipeng He; Song Liu; Ning Mao; Zhonghui Zhang; Chang-Lian Peng; Jianbin Lai; Chengwei Yang
Journal:  Plant Cell       Date:  2022-09-27       Impact factor: 12.085

2.  Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions.

Authors:  James M Daley; Nozomi Tomimatsu; Grace Hooks; Weibin Wang; Adam S Miller; Xiaoyu Xue; Kevin A Nguyen; Hardeep Kaur; Elizabeth Williamson; Bipasha Mukherjee; Robert Hromas; Sandeep Burma; Patrick Sung
Journal:  Nat Commun       Date:  2020-06-18       Impact factor: 14.919

3.  Long noncoding RNAs: p53's secret weapon in the fight against cancer?

Authors:  Emily Dangelmaier; Sarah B Lazar; Ashish Lal
Journal:  PLoS Biol       Date:  2019-02-13       Impact factor: 8.029

4.  Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance.

Authors:  Lei Liu; Yuanyuan Chen; Yijuan Huang; Kun Cao; Tingting Liu; Hui Shen; Jianguo Cui; Bailong Li; Jianming Cai; Fu Gao; Yanyong Yang
Journal:  Mol Cancer       Date:  2021-07-05       Impact factor: 27.401
  4 in total

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