Literature DB >> 29183893

Brief psychotic episode in a patient with chromosome 2q37 microdeletion syndrome.

Kevin Lally1, Nuraini Ibrahim1,2, Mary Kelly1,2, Gautam Gulati1.   

Abstract

A 21-year-old woman with moderate learning disability secondary to chromosome 2 microdeletion at q37 was admitted to a general adult psychiatric ward following a period of agitation with incessant pressure of speech, nihilistic delusions and worsening of sleep and eating patterns. Her presentation was preceded for a number of weeks by social stressors of an ill family member and another family member moving away. She had also been diagnosed and treated for a respiratory infection several weeks prior to presentation. Her presentation improved with low-dose antipsychotic medication and parallel input from the general adult mental health team and the psychiatry of intellectual disability team. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  congenital disorders; genetics; psychotic disorders (incl schizophrenia); therapeutic indications

Mesh:

Year:  2017        PMID: 29183893      PMCID: PMC5720329          DOI: 10.1136/bcr-2017-221012

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

1.  Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q.

Authors:  T Paunio; J Ekelund; T Varilo; A Parker; I Hovatta; J A Turunen; K Rinard; A Foti; J D Terwilliger; H Juvonen; J Suvisaari; R Arajärvi; J Suokas; T Partonen; J Lönnqvist; J Meyer; L Peltonen
Journal:  Hum Mol Genet       Date:  2001-12-15       Impact factor: 6.150

2.  Genome-wide scan in a large complex pedigree with predominantly male schizophrenics from the island of Kosrae: evidence for linkage to chromosome 2q.

Authors:  E M Wijsman; E A Rosenthal; D Hall; M L Blundell; C Sobin; S C Heath; R Williams; M J Brownstein; J A Gogos; M Karayiorgou
Journal:  Mol Psychiatry       Date:  2003-07       Impact factor: 15.992

3.  The first familial case of inherited 2q37.3 interstitial deletion with isolated skeletal abnormalities including brachydactyly type E and short stature.

Authors:  Nolwenn Jean-Marçais; Matthieu Decamp; Marion Gérard; Virginie Ribault; Joris Andrieux; Marie-Laure Kottler; Ghislaine Plessis
Journal:  Am J Med Genet A       Date:  2014-11-17       Impact factor: 2.802

4.  2q37.3 Deletion Syndrome: Two Cases with Highly Distinctive Facial Phenotype, Discordant Association with Schizophrenic Psychosis, and Shared Deletion Breakpoint Region on 2q37.3.

Authors:  Yasmin Mehraein; Martina Pfob; Ortrud Steinlein; Eric Aichinger; Marlene Eggert; Valerie Bubendorff; Adelina Mannhart; Stefan Müller
Journal:  Cytogenet Genome Res       Date:  2015-06-19       Impact factor: 1.636

5.  Linkage analysis of a completely ascertained sample of familial schizophrenics and bipolars from Palau, Micronesia.

Authors:  Lambertus Klei; Silviu-Alin Bacanu; Marina Myles-Worsley; Brandi Galke; Weiting Xie; Josepha Tiobech; Caleb Otto; Kathyrn Roeder; Bernie Devlin; William Byerley
Journal:  Hum Genet       Date:  2005-05-25       Impact factor: 4.132

6.  Neuropsychological profiles of patients with 2q37.3 deletion associated with developmental dyspraxia.

Authors:  Kaeko Ogura; Kenzo Takeshita; Chikako Arakawa; Keiko Shimojima; Toshiyuki Yamamoto
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2014-10-20       Impact factor: 3.568

7.  The 2q37-deletion syndrome: an update of the clinical spectrum including overweight, brachydactyly and behavioural features in 14 new patients.

Authors:  Camille Leroy; Emilie Landais; Sylvain Briault; Albert David; Olivier Tassy; Nicolas Gruchy; Bruno Delobel; Marie-José Grégoire; Bruno Leheup; Laurence Taine; Didier Lacombe; Marie-Ange Delrue; Annick Toutain; Agathe Paubel; Francine Mugneret; Christel Thauvin-Robinet; Stéphanie Arpin; Cedric Le Caignec; Philippe Jonveaux; Mylène Beri; Nathalie Leporrier; Jacques Motte; Caroline Fiquet; Olivier Brichet; Monique Mozelle-Nivoix; Pascal Sabouraud; Nathalie Golovkine; Nathalie Bednarek; Dominique Gaillard; Martine Doco-Fenzy
Journal:  Eur J Hum Genet       Date:  2012-10-17       Impact factor: 4.246

Review 8.  Chromosome 2q37 deletion: clinical and molecular aspects.

Authors:  Rena E Falk; Kari A Casas
Journal:  Am J Med Genet C Semin Med Genet       Date:  2007-11-15       Impact factor: 3.908

  8 in total

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