J Alcántara-González1, P Boixeda2, M T Truchuelo-Díez3, N Jiménez-Gómez3, B Pérez-García3, L Pérez-Carmona4, P Jaén Olasolo2. 1. Servicio de Dermatología, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid, España. Electronic address: jalcantarag@hotmail.es. 2. Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Madrid, España; Universidad de Alcalá, Alcalá de Henares, Madrid, España. 3. Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Madrid, España. 4. Servicio de Dermatología, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid, España.
Abstract
INTRODUCTION AND OBJECTIVE: Capillary malformations are the most common vascular malformations in childhood. The current treatment of choice is pulsed dye laser (PDL) therapy, but this frequently does not result in complete resolution. The search for alternative treatment strategies thus continues. In this study we describe our experience with the use of sequential dual-wavelength PDL and Nd:YAG laser therapy in patients with capillary malformations. MATERIAL AND METHODS: We conducted a retrospective, descriptive study of patients with capillary malformations treated with dual-wavelength PDL and Nd:YAG laser therapy between 2006 and 2011. Four dermatologists rated the effectiveness of treatment on a scale of 10 to 0. We also investigated the potential value of the following factors as predictors of better treatment response: sex, malformation size and color, and presence of associated hypertrophy. Adverse effects were also analyzed. RESULTS: We studied 71 patients and most of them experienced a statistically significant improvement after treatment. More favorable responses were observed for violaceous malformations, lesions with associated hypertrophy, and smaller lesions. Adverse effects were reported for 26.76% of patients, and the most common effect was the appearance of isolated areas of skin atrophy. CONCLUSIONS: We consider that sequential dual-wavelength PDL and ND:YAG laser therapy is an effective alternative for treating capillary malformations in selected patients.
INTRODUCTION AND OBJECTIVE:Capillary malformations are the most common vascular malformations in childhood. The current treatment of choice is pulsed dye laser (PDL) therapy, but this frequently does not result in complete resolution. The search for alternative treatment strategies thus continues. In this study we describe our experience with the use of sequential dual-wavelength PDL and Nd:YAG laser therapy in patients with capillary malformations. MATERIAL AND METHODS: We conducted a retrospective, descriptive study of patients with capillary malformations treated with dual-wavelength PDL and Nd:YAG laser therapy between 2006 and 2011. Four dermatologists rated the effectiveness of treatment on a scale of 10 to 0. We also investigated the potential value of the following factors as predictors of better treatment response: sex, malformation size and color, and presence of associated hypertrophy. Adverse effects were also analyzed. RESULTS: We studied 71 patients and most of them experienced a statistically significant improvement after treatment. More favorable responses were observed for violaceous malformations, lesions with associated hypertrophy, and smaller lesions. Adverse effects were reported for 26.76% of patients, and the most common effect was the appearance of isolated areas of skin atrophy. CONCLUSIONS: We consider that sequential dual-wavelength PDL and ND:YAG laser therapy is an effective alternative for treating capillary malformations in selected patients.
Authors: Luigi Bennardo; Gaia Fasano; Federica Tamburi; Elena Zappia; Francesco Rizzuto; Steven Paul Nisticò; Giovanni Cannarozzo Journal: Medicina (Kaunas) Date: 2022-01-12 Impact factor: 2.430