Literature DB >> 29181162

Assessing predictors for the success of GnRH antagonist protocol in reproductive women in IVF/ICSI - in fresh cycles.

An-Cong Wang1,2, Ying Wang3, Feng-Xia Wu4, Dong-Yi Zhu1,2.   

Abstract

The aim of the present study was to evaluate the factors that affect the success rate of gonadotropin-releasing hormone antagonist on in vitro fertilization/intracytoplasmic sperm injection cycles. Multivariate analysis was performed to assess the factors that influence the outcomes, such as oocytes retrieved, and the success of pregnancy. The results showed that E2, P on human chorionic gonadotropin (HCG) day and body mass index (BMI) were positively correlated with the number of oocytes retrieved (P=0.001, P=0.024, P=0.017, respectively). The duration of infertility as well as the luteinizing hormone on HCG day were negatively correlated with the number of oocytes (P=0.048, P=0.002, respectively). The age of the women and P on HCG day were negatively correlated with successful pregnancy (P<0.001, P=0.022). In conclusion, some parameters, such as E2, P, and LH on the HCG day, as well as age and BMI, may affect treatment outcomes.

Entities:  

Keywords:  GnRH antagonist; IVF/ICSI-ET; clinical pregnancy; fresh cycle

Year:  2017        PMID: 29181162      PMCID: PMC5700393          DOI: 10.3892/br.2017.984

Source DB:  PubMed          Journal:  Biomed Rep        ISSN: 2049-9434


  34 in total

Review 1.  Embryo implantation and GnRH antagonists: embryo implantation: the Rubicon for GnRH antagonists.

Authors:  E R Hernandez
Journal:  Hum Reprod       Date:  2000-06       Impact factor: 6.918

2.  Follicular growth and oocyte maturation in GnRH agonist and antagonist protocols for in vitro fertilisation and embryo transfer.

Authors:  Raffaella Depalo; Filomenamila Lorusso; Marcella Palmisano; Emma Bassi; Ilaria Totaro; Margherita Vacca; Paolo Trerotoli; Paola Masciandaro; Luigi Selvaggi
Journal:  Gynecol Endocrinol       Date:  2009-05       Impact factor: 2.260

3.  Association of serum estradiol levels on the day of hCG administration with pregnancy rates and embryo scores in fresh ICSI/ET cycles down regulated with either GnRH agonists or GnRH antagonists.

Authors:  Elif Aylin Taşkin; Cem Somer Atabekoğlu; Nati Musali; Derya Öztuna; Murat Sönmezer
Journal:  Arch Gynecol Obstet       Date:  2013-08-04       Impact factor: 2.344

4.  A cost-effectiveness analysis of in-vitro fertilization by maternal age and number of treatment attempts.

Authors:  Alison Griffiths; Suzanne M Dyer; Sarah J Lord; Chris Pardy; Ian S Fraser; Simon Eckermann
Journal:  Hum Reprod       Date:  2010-01-26       Impact factor: 6.918

5.  Endometrial thickness: a predictor of implantation in ovum recipients?

Authors:  H I Abdalla; A A Brooks; M R Johnson; A Kirkland; A Thomas; J W Studd
Journal:  Hum Reprod       Date:  1994-02       Impact factor: 6.918

6.  The individualized choice of embryo transfer timing for patients with elevated serum progesterone level on the HCG day in IVF/ICSI cycles: a prospective randomized clinical study.

Authors:  Shuo Yang; Tianshu Pang; Rong Li; Rui Yang; Xiumei Zhen; Xinna Chen; Haiyan Wang; Caihong Ma; Ping Liu; Jie Qiao
Journal:  Gynecol Endocrinol       Date:  2015-01-05       Impact factor: 2.260

7.  Progesterone levels on the day of human chorionic gonadotropin do not predict pregnancy outcome from the transfer of fresh or cryopreserved embryos from the same cohort.

Authors:  D V Moffitt; J T Queenan; R Shaw; S J Muasher
Journal:  Fertil Steril       Date:  1997-02       Impact factor: 7.329

8.  Effects of high progesterone on outcomes of in vitro fertilization-embryo transfer in patients with different ovarian responses.

Authors:  Peng-fen Li; Hong Zhu; Li Tan; Dong-mei Zhao; Li-ying Ma; Yun-gai Xiang; Dan Zhang; Qian Dou; Na Lu
Journal:  Syst Biol Reprod Med       Date:  2015-04-27       Impact factor: 3.061

Review 9.  World Health Organization reference values for human semen characteristics.

Authors:  Trevor G Cooper; Elizabeth Noonan; Sigrid von Eckardstein; Jacques Auger; H W Gordon Baker; Hermann M Behre; Trine B Haugen; Thinus Kruger; Christina Wang; Michael T Mbizvo; Kirsten M Vogelsong
Journal:  Hum Reprod Update       Date:  2009-11-24       Impact factor: 15.610

10.  Association between serum estradiol level on the hCG administration day and IVF-ICSI outcome.

Authors:  Mustafa Kara; Tayfun Kutlu; Kenan Sofuoglu; Belgin Devranoglu; Tansel Cetinkaya
Journal:  Iran J Reprod Med       Date:  2012-01
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