| Literature DB >> 29181160 |
Yoriko Murata1, Yasuhiro Hata2, Yoshihiro Noda2, Satoshi Matsusaka2, Naoki Fukui3, Tomohito Kadota3, Jun Iwata4, Takuya Machida5, Takuji Yamagami1.
Abstract
The present case study describes a rare case of secondary central nervous system (CNS) lymphoma that infiltrated the dura and leptomeninges around the area injured by subarachnoid hemorrhage and subsequent aneurysmal clipping. Invasion of the CNS was observed by computed tomography as slurred fissures of the right parietal lobe adjacent to the surgery area. Subdural and subarachnoid enhancement overlapping the area injured by past surgical procedures was observed by contrast-enhanced magnetic resonance imaging. Surgical resection revealed B-cell lymphoma infiltrating the dura and leptomeninges surrounding the post-hemorrhagic area. The patient was subsequently diagnosed with systemic lymphoma and bone marrow invasion, and multiple lymph node swelling. To the best of our knowledge, this is the first report of malignant lymphoma involving the CNS overlapping a previously injured area.Entities:
Keywords: central nervous system invasion; disrupted blood brain barrier; history of subarachnoid hemorrhage; malignant lymphoma
Year: 2017 PMID: 29181160 PMCID: PMC5700395 DOI: 10.3892/br.2017.981
Source DB: PubMed Journal: Biomed Rep ISSN: 2049-9434