| Literature DB >> 2917988 |
C Sass1, M Briand, S Benslimane, M Renaud, Y Briand.
Abstract
Two cDNA clones were isolated, one corresponding to the mRNA coding for lactate dehydrogenase-M (LDH-M), the other to the mRNA coding for lactate dehydrogenase-H (LDH-H). The cDNA inserts consist of the entire open reading frame for LDH-M and a partial sequence, from amino acid 117 to 332, for LDH-H. Using these two clones as probes we demonstrate that: (a) the abundance of mRNA is muscle-type dependent; (b) the ratio M/H subunit for protein and mRNA is well related in the muscles studied; and (c) the M + H mRNA level is not relative to the total LDH activity.Entities:
Mesh:
Substances:
Year: 1989 PMID: 2917988
Source DB: PubMed Journal: J Biol Chem ISSN: 0021-9258 Impact factor: 5.157