Literature DB >> 29179096

Cross-talk between protein synthesis, energy metabolism and autophagy in cancer.

Lisa M Lindqvist1, Kristofferson Tandoc2, Ivan Topisirovic3, Luc Furic4.   

Abstract

Translation is a pivotal step in the regulation of gene expression as well as one of the most energy consuming processes in the cell. Dysregulation of translation caused by the aberrant function of upstream signaling pathways and/or perturbations in the expression or function of components of the translation machinery is frequent in cancer. In this review, we discuss emerging findings that highlight hitherto unappreciated aspects of signaling to the translation apparatus with the particular focus on emerging connections between protein synthesis, autophagy and energy homeostasis in cancer.
Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

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Year:  2017        PMID： 29179096      PMCID： PMC5869074          DOI： 10.1016/j.gde.2017.11.003

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  64 in total

1.  Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.

Authors:  Qian Wang; Charles G Bailey; Cynthia Ng; Jessamy Tiffen; Annora Thoeng; Vineet Minhas; Melanie L Lehman; Stephen C Hendy; Grant Buchanan; Colleen C Nelson; John E J Rasko; Jeff Holst
Journal:  Cancer Res       Date:  2011-10-17       Impact factor: 12.701

2.  Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

Authors:  Jun Onodera; Yoshinori Ohsumi
Journal:  J Biol Chem       Date:  2005-07-15       Impact factor: 5.157

3.  The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation.

Authors:  Gabriel Leprivier; Marc Remke; Barak Rotblat; Adrian Dubuc; Abigail-Rachele F Mateo; Marcel Kool; Sameer Agnihotri; Amal El-Naggar; Bin Yu; Syam Prakash Somasekharan; Brandon Faubert; Gaëlle Bridon; Cristina E Tognon; Joan Mathers; Ryan Thomas; Amy Li; Adi Barokas; Brian Kwok; Mary Bowden; Stephanie Smith; Xiaochong Wu; Andrey Korshunov; Thomas Hielscher; Paul A Northcott; Jason D Galpin; Christopher A Ahern; Ye Wang; Martin G McCabe; V Peter Collins; Russell G Jones; Michael Pollak; Olivier Delattre; Martin E Gleave; Eric Jan; Stefan M Pfister; Christopher G Proud; W Brent Derry; Michael D Taylor; Poul H Sorensen
Journal:  Cell       Date:  2013-05-23       Impact factor: 41.582

Review 4.  The scanning mechanism of eukaryotic translation initiation.

Authors:  Alan G Hinnebusch
Journal:  Annu Rev Biochem       Date:  2014-01-29       Impact factor: 23.643

5.  DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs.

Authors:  Michelle Badura; Steve Braunstein; Jiri Zavadil; Robert J Schneider
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-29       Impact factor: 11.205

6.  Current questions and possible controversies in autophagy.

Authors:  L M Lindqvist; A K Simon; E H Baehrecke
Journal:  Cell Death Discov       Date:  2015-11-09

7.  mTORC1 Balances Cellular Amino Acid Supply with Demand for Protein Synthesis through Post-transcriptional Control of ATF4.

Authors:  Yeonwoo Park; Andrea Reyna-Neyra; Lucas Philippe; Carson C Thoreen
Journal:  Cell Rep       Date:  2017-05-09       Impact factor: 9.423

8.  A translation initiation element specific to mRNAs with very short 5'UTR that also regulates transcription.

Authors:  Rofa Elfakess; Rivka Dikstein
Journal:  PLoS One       Date:  2008-08-28       Impact factor: 3.240

9.  ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

Authors:  Ryan C Russell; Ye Tian; Haixin Yuan; Hyun Woo Park; Yu-Yun Chang; Joungmok Kim; Haerin Kim; Thomas P Neufeld; Andrew Dillin; Kun-Liang Guan
Journal:  Nat Cell Biol       Date:  2013-05-19       Impact factor: 28.824

10.  Elongation factor 2 kinase promotes cell survival by inhibiting protein synthesis without inducing autophagy.

Authors:  Claire E J Moore; Xuemin Wang; Jianling Xie; Jo Pickford; John Barron; Sergio Regufe da Mota; Matthias Versele; Christopher G Proud
Journal:  Cell Signal       Date:  2016-01-18       Impact factor: 4.315
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  38 in total

1.  eIF4A Inhibitors Suppress Cell-Cycle Feedback Response and Acquired Resistance to CDK4/6 Inhibition in Cancer.

Authors:  Tim Kong; Yibo Xue; Regina Cencic; Xianbing Zhu; Anie Monast; Zheng Fu; Virginie Pilon; Veena Sangwan; Marie-Christine Guiot; William D Foulkes; John A Porco; Morag Park; Jerry Pelletier; Sidong Huang
Journal:  Mol Cancer Ther       Date:  2019-08-08       Impact factor: 6.261

Review 2.  Normal and Neoplastic Growth Suppression by the Extended Myc Network.

Authors:  Edward V Prochownik; Huabo Wang
Journal:  Cells       Date:  2022-02-21       Impact factor: 6.600

Review 3.  MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus.

Authors:  Bérénice A Benayoun; Changhan Lee
Journal:  Bioessays       Date:  2019-08-05       Impact factor: 4.345

4.  Lower oxygen consumption and Complex I activity in mitochondria isolated from skeletal muscle of fetal sheep with intrauterine growth restriction.

Authors:  Alexander L Pendleton; Andrew T Antolic; Amy C Kelly; Melissa A Davis; Leticia E Camacho; Kevin Doubleday; Miranda J Anderson; Paul R Langlais; Ronald M Lynch; Sean W Limesand
Journal:  Am J Physiol Endocrinol Metab       Date:  2020-05-12       Impact factor: 4.310

5.  Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration.

Authors:  Konstantinos Sousounis; Donald M Bryant; Jose Martinez Fernandez; Samuel S Eddy; Stephanie L Tsai; Gregory C Gundberg; Jihee Han; Katharine Courtemanche; Michael Levin; Jessica L Whited
Journal:  Elife       Date:  2020-03-06       Impact factor: 8.140

6.  Might hyperbaric oxygen therapy (HBOT) reduce renal injury in diabetic people with diabetes mellitus? From preclinical models to human metabolomics.

Authors:  Lauren E Harrison; Charles Giardina; Lawrence E Hightower; Caesar Anderson; George A Perdrizet
Journal:  Cell Stress Chaperones       Date:  2018-10-30       Impact factor: 3.667

Review 7.  Translation acrobatics: how cancer cells exploit alternate modes of translational initiation.

Authors:  Ashwin Sriram; Jonathan Bohlen; Aurelio A Teleman
Journal:  EMBO Rep       Date:  2018-09-17       Impact factor: 8.807

8.  Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast.

Authors:  Athanasios Litsios; Daphne H E W Huberts; Hanna M Terpstra; Paolo Guerra; Alexander Schmidt; Katarzyna Buczak; Alexandros Papagiannakis; Mattia Rovetta; Johan Hekelaar; Georg Hubmann; Marten Exterkate; Andreas Milias-Argeitis; Matthias Heinemann
Journal:  Nat Cell Biol       Date:  2019-11-04       Impact factor: 28.824

Review 9.  Eukaryotic elongation factor-2 kinase (eEF2K) signaling in tumor and microenvironment as a novel molecular target.

Authors:  Didem Karakas; Bulent Ozpolat
Journal:  J Mol Med (Berl)       Date:  2020-05-07       Impact factor: 4.599

Review 10.  Amino Acid Metabolic Vulnerabilities in Acute and Chronic Myeloid Leukemias.

Authors:  Aboli Bhingarkar; Hima V Vangapandu; Sanjay Rathod; Keito Hoshitsuki; Christian A Fernandez
Journal:  Front Oncol       Date:  2021-07-01       Impact factor: 6.244
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