Literature DB >> 29177936

Is bacterial vaginosis a disease?

Gregor Reid1.   

Abstract

Bacterial vaginosis (BV) has been described as a disease, a disorder, a vaginal inflammation, an infection, a microbial dysbiosis, a condition, and in some women, a normal situation. In order to fit the definition of a disease, BV would have to be a disorder of function that produces specific signs or symptoms or affects the vagina in an aberrant way. Yet, there is little consistency in patients reporting signs and symptoms when BV is diagnosed, nor the appearance of aberrations to the vagina. If BV is not a disease, there are implications for its management and coverage of treatment costs, and for the conclusions drawn in a multitude of previous studies. It is time for BV to be redefined and for the various subsets to be given a separate terminology with specific methods of diagnosis and appropriate treatment and preventive strategies.

Entities:  

Keywords:  Bacterial vaginosis; Disease; Dysbiosis; Inflammation; Microbiota

Mesh:

Year:  2017        PMID: 29177936     DOI: 10.1007/s00253-017-8659-9

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  11 in total

Review 1.  Towards a deeper understanding of the vaginal microbiota.

Authors:  Michael France; Madeline Alizadeh; Sarah Brown; Bing Ma; Jacques Ravel
Journal:  Nat Microbiol       Date:  2022-03-04       Impact factor: 30.964

2.  Complement Activation During Early Pregnancy and Clinical Predictors of Preterm Birth in African American Women.

Authors:  Alexis B Dunn; Anne L Dunlop; Andrew H Miller; Carol J Hogue; Jordan M Crofton; Elizabeth J Corwin
Journal:  J Perinat Neonatal Nurs       Date:  2019 Oct/Dec       Impact factor: 1.638

Review 3.  The relationship between sex hormones, the vaginal microbiome and immunity in HIV-1 susceptibility in women.

Authors:  Jocelyn M Wessels; Allison M Felker; Haley A Dupont; Charu Kaushic
Journal:  Dis Model Mech       Date:  2018-08-28       Impact factor: 5.758

4.  The Need to Focus on Therapy Instead of Associations.

Authors:  Gregor Reid
Journal:  Front Cell Infect Microbiol       Date:  2019-09-12       Impact factor: 5.293

5.  Comparative genomics of human Lactobacillus crispatus isolates reveals genes for glycosylation and glycogen degradation: implications for in vivo dominance of the vaginal microbiota.

Authors:  Charlotte van der Veer; Rosanne Y Hertzberger; Sylvia M Bruisten; Hanne L P Tytgat; Jorne Swanenburg; Alie de Kat Angelino-Bart; Frank Schuren; Douwe Molenaar; Gregor Reid; Henry de Vries; Remco Kort
Journal:  Microbiome       Date:  2019-03-29       Impact factor: 14.650

6.  Association of bacterial vaginosis with periodontitis in a cross-sectional American nationwide survey.

Authors:  Cláudia Escalda; João Botelho; José João Mendes; Vanessa Machado
Journal:  Sci Rep       Date:  2021-01-12       Impact factor: 4.379

Review 7.  The reproductive tract microbiota in pregnancy.

Authors:  Karen Grewal; David A MacIntyre; Phillip R Bennett
Journal:  Biosci Rep       Date:  2021-09-30       Impact factor: 3.840

Review 8.  Has knowledge of the vaginal microbiome altered approaches to health and disease?

Authors:  Gregor Reid
Journal:  F1000Res       Date:  2018-04-13

9.  The vaginal microbiota in the course of bacterial vaginosis treatment.

Authors:  Romy D Zwittink; Ellen H A van den Munckhof; Maurine A Leverstein-van Hall; Kim Boers; Anco Molijn; Cornelis W Knetsch; Ed J Kuijper
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2020-10-07       Impact factor: 3.267

Review 10.  Bacterial Vaginosis: What Do We Currently Know?

Authors:  Linda Abou Chacra; Florence Fenollar; Khoudia Diop
Journal:  Front Cell Infect Microbiol       Date:  2022-01-18       Impact factor: 5.293

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