Literature DB >> 29177796

Molecular and Cellular Mechanisms Involved in Mesenchymal Stem Cell-Based Therapy of Inflammatory Bowel Diseases.

Bojana Simovic Markovic1, Tatjana Kanjevac2, C Randall Harrell3, Marina Gazdic4, Crissy Fellabaum3, Nebojsa Arsenijevic1, Vladislav Volarevic5.   

Abstract

Mesenchymal stem cells (MSCs) are promising resource for the therapy of inflammatory bowel diseases (IBDs) on the grounds of their differentiation capabilities and immuno-modulatory characteristics. Results of clinical studies indicate that local application of MSCs is a secure and beneficial approach for the treatment of perianal fistulas while systemic application of MSCs leads to the attenuation or aggravation of IBDs. Herein, we emphasized molecular mechanisms and approaches that should improve efficacy of MSC-based therapy of IBDs.

Entities:  

Keywords:  Cell-based therapy; Chron’s disease; Mesenchymal stem cells; Transplantation; Ulcerative colitis

Mesh：

Year:  2018        PMID： 29177796     DOI： 10.1007/s12015-017-9789-2

Source DB:  PubMed          Journal:  Stem Cell Rev Rep        ISSN： 2629-3277            Impact factor:   5.739


  79 in total

1.  Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study.

Authors:  Marjolijn Duijvestein; Anne Christine W Vos; Helene Roelofs; Manon E Wildenberg; Barbara B Wendrich; Henricus W Verspaget; Engelina M C Kooy-Winkelaar; Frits Koning; Jaap Jan Zwaginga; Herma H Fidder; Auke P Verhaar; Willem E Fibbe; Gijs R van den Brink; Daniel W Hommes
Journal:  Gut       Date:  2010-10-04       Impact factor: 23.059

2.  Human adipose tissue is a source of multipotent stem cells.

Authors:  Patricia A Zuk; Min Zhu; Peter Ashjian; Daniel A De Ugarte; Jerry I Huang; Hiroshi Mizuno; Zeni C Alfonso; John K Fraser; Prosper Benhaim; Marc H Hedrick
Journal:  Mol Biol Cell       Date:  2002-12       Impact factor: 4.138

3.  Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine.

Authors:  T T MacDonald; P Hutchings; M Y Choy; S Murch; A Cooke
Journal:  Clin Exp Immunol       Date:  1990-08       Impact factor: 4.330

4.  Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease.

Authors:  Rachele Ciccocioppo; Maria Ester Bernardo; Adele Sgarella; Rita Maccario; Maria Antonietta Avanzini; Cristina Ubezio; Antonella Minelli; Costanza Alvisi; Alessandro Vanoli; Fabrizio Calliada; Paolo Dionigi; Cesare Perotti; Franco Locatelli; Gino Roberto Corazza
Journal:  Gut       Date:  2011-01-21       Impact factor: 23.059

5.  Various types of stem cells, including a population of very small embryonic-like stem cells, are mobilized into peripheral blood in patients with Crohn's disease.

Authors:  Wojciech Marlicz; Ewa Zuba-Surma; Magda Kucia; Wojciech Blogowski; Teresa Starzynska; Mariusz Z Ratajczak
Journal:  Inflamm Bowel Dis       Date:  2012-01-11       Impact factor: 5.325

Review 6.  Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation.

Authors:  Ana Izcue; Janine L Coombes; Fiona Powrie
Journal:  Immunol Rev       Date:  2006-08       Impact factor: 12.988

7.  Adipose-Derived Mesenchymal Stem Cells Ameliorate Ulcerative Colitis Through miR-1236 Negatively Regulating the Expression of Retinoid-Related Orphan Receptor Gamma.

Authors:  Ying Zhang; Yu Jin; Yan Lin; Lian-jie Lin; Yong Cao; Dong-xu Wang; Chang-qing Zheng
Journal:  DNA Cell Biol       Date:  2015-08-03       Impact factor: 3.311

Review 8.  Regulatory T cells in inflammatory bowel disease.

Authors:  Elisa K Boden; Scott B Snapper
Journal:  Curr Opin Gastroenterol       Date:  2008-11       Impact factor: 3.287

9.  Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism.

Authors:  Farida Djouad; Louis-Marie Charbonnier; Carine Bouffi; Pascale Louis-Plence; Claire Bony; Florence Apparailly; Céline Cantos; Christian Jorgensen; Danièle Noël
Journal:  Stem Cells       Date:  2007-05-17       Impact factor: 6.277

10.  Infectious gastroenteritis and risk of developing inflammatory bowel disease.

Authors:  Chad K Porter; David R Tribble; Pablo A Aliaga; Heather A Halvorson; Mark S Riddle
Journal:  Gastroenterology       Date:  2008-06-05       Impact factor: 22.682
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  12 in total

Review 1.  Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?

Authors:  Eduardo J Villablanca; Katja Selin; Charlotte R H Hedin
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2022-04-19       Impact factor: 73.082

2.  Female Age Affects the Mesenchymal Stem Cell Characteristics of Aspirated Follicular Cells in the In Vitro Fertilization Programme.

Authors:  Irma Virant-Klun; S Omejec; M Stimpfel; P Skerl; S Novakovic; N Jancar; E Vrtacnik-Bokal
Journal:  Stem Cell Rev Rep       Date:  2019-08       Impact factor: 5.739

3.  IGF-1C hydrogel improves the therapeutic effects of MSCs on colitis in mice through PGE2-mediated M2 macrophage polarization.

Authors:  Xiaocang Cao; Liyun Duan; Huixing Hou; Yue Liu; Shang Chen; Shuaiqiang Zhang; Yuanyuan Liu; Chen Wang; Xin Qi; Na Liu; Zhibo Han; Dekui Zhang; Zhong-Chao Han; Zhikun Guo; Qiang Zhao; Zongjin Li
Journal:  Theranostics       Date:  2020-06-19       Impact factor: 11.556

4.  Intercellular adhesion molecule-1 enhances the therapeutic effects of MSCs in a dextran sulfate sodium-induced colitis models by promoting MSCs homing to murine colons and spleens.

Authors:  Xin Li; Qian Wang; Li Ding; Yu-Xing Wang; Zhi-Dong Zhao; Ning Mao; Chu-Tse Wu; Hua Wang; Heng Zhu; Shou-Bin Ning
Journal:  Stem Cell Res Ther       Date:  2019-08-23       Impact factor: 6.832

5.  SDF-1/CXCR4 axis enhances the immunomodulation of human endometrial regenerative cells in alleviating experimental colitis.

Authors:  Xiang Li; Xu Lan; Yiming Zhao; Grace Wang; Ganggang Shi; Hongyue Li; Yonghao Hu; Xiaoxi Xu; Baoren Zhang; Kui Ye; Xiangying Gu; Caigan Du; Hao Wang
Journal:  Stem Cell Res Ther       Date:  2019-07-08       Impact factor: 6.832

6.  Adipose-Derived Stem Cells From Patients With Ulcerative Colitis Exhibit Impaired Immunosuppressive Function.

Authors:  Xiaoyun Wu; Yongxu Mu; Jingyi Yao; Fuhong Lin; Daocheng Wu; Zhijie Ma
Journal:  Front Cell Dev Biol       Date:  2022-02-18

7.  IL-1β pre-stimulation enhances the therapeutic effects of endometrial regenerative cells on experimental colitis.

Authors:  Dingding Yu; Yiming Zhao; Hongda Wang; Dejun Kong; Wang Jin; Yonghao Hu; Yafei Qin; Baoren Zhang; Xiang Li; Jingpeng Hao; Guangming Li; Hao Wang
Journal:  Stem Cell Res Ther       Date:  2021-06-05       Impact factor: 6.832

Review 8.  Cannabis and Canabidinoids on the Inflammatory Bowel Diseases: Going Beyond Misuse.

Authors:  Antonelly Cassio Alves de Carvalho; Gabriela Achete de Souza; Samylla Vaz de Marqui; Élen Landgraf Guiguer; Adriano Cressoni Araújo; Claudio José Rubira; Ricardo de Alvares Goulart; Uri Adrian Prync Flato; Patricia Cincotto Dos Santos Bueno; Rogério Leone Buchaim; Sandra M Barbalho
Journal:  Int J Mol Sci       Date:  2020-04-22       Impact factor: 5.923

9.  Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice.

Authors:  Jun Xu; Xiaofang Wang; Jiaye Chen; Shengbo Chen; Zhijun Li; Hongbin Liu; Yang Bai; Fachao Zhi
Journal:  Theranostics       Date:  2020-10-30       Impact factor: 11.556

10.  Adipose mesenchymal stromal/stem cells expanded by a GMP compatible protocol displayed improved adhesion on cancer cells in flow conditions.

Authors:  Francesco Agostini; Carla Vicinanza; Federica Di Cintio; Monica Battiston; Elisabetta Lombardi; Giulia Golinelli; Cristina Durante; Giuseppe Toffoli; Massimo Dominici; Mario Mazzucato
Journal:  Ann Transl Med       Date:  2020-04
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