Andrea Franzini1, Rebecca Ranieri2,3, Orsola Gambini2,3, Giuseppe Messina4. 1. Department of Neurosurgery, Fondazione IRCCS Istituto Nazionale Neurologico Carlo Besta, Via Giovanni Celoria 11, 20133, Milan, Italy. andrea.franzini1@hotmail.it. 2. Department of Health Sciences, Università Degli Studi di Milano, Milan, Italy. 3. Department of Mental Health, San Paolo Hospital, Milan, Italy. 4. Department of Neurosurgery, Fondazione IRCCS Istituto Nazionale Neurologico Carlo Besta, Via Giovanni Celoria 11, 20133, Milan, Italy.
Abstract
BACKGROUND: Twiddler's syndrome consists of rotation or manipulation of an implantable pulse generator (IPG) in its subcutaneous pocket by a patient, thus causing hardware malfunction. METHODS: This syndrome is being reported more frequently in patients treated with deep brain stimulation (DBS). RESULTS: We report the case of a woman who had received bed nucleus of stria terminalis (BNST) electrodes for obsessive-compulsive disorder (OCD) and developed twiddler's syndrome a few months after surgery, causing hardware malfunction due to obsessive manipulation of the IPG. CONCLUSION: The patient did not have compulsions related to touching objects at admission, thus making it difficult to foresee and prevent TS.
BACKGROUND:Twiddler's syndrome consists of rotation or manipulation of an implantable pulse generator (IPG) in its subcutaneous pocket by a patient, thus causing hardware malfunction. METHODS: This syndrome is being reported more frequently in patients treated with deep brain stimulation (DBS). RESULTS: We report the case of a woman who had received bed nucleus of stria terminalis (BNST) electrodes for obsessive-compulsive disorder (OCD) and developed twiddler's syndrome a few months after surgery, causing hardware malfunction due to obsessive manipulation of the IPG. CONCLUSION: The patient did not have compulsions related to touching objects at admission, thus making it difficult to foresee and prevent TS.
Entities:
Keywords:
Deep brain stimulation; Obsessive-compulsive disorder; Twiddler’s syndrome
Authors: In-Ho Jung; Kyung Won Chang; So Hee Park; Won Seok Chang; Hyun Ho Jung; Jin Woo Chang Journal: Front Aging Neurosci Date: 2022-04-07 Impact factor: 5.702