| Literature DB >> 29177586 |
Hyung Sik Kim1, Jin Woo Lee1, Hari Jang1, Thi Phuong Linh Le1, Jun Gu Kim1, Moon Soon Lee2, Jin Tae Hong1, Mi Kyeong Lee1, Bang Yeon Hwang3.
Abstract
A new phenolic amide, named cis-terrestriamide (7), together with ten known compounds (1-6, 8-11), were isolated from the methanolic extract of the fruits of Tribulus terrestris. The structure of 7 was elucidated on the basis of extensive analyses of 1D and 2D nuclear magnetic resonance spectroscopic and high resolution mass spectrometry data. Compounds 1, 2, 5, 6, 8, 9, and 11 exhibited inhibitory effects on the lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 cells, with IC50 values of 18.7-49.4 μM.Entities:
Keywords: Phenolic amide, Nitric oxide production inhibitor; Tribulus terrestris; Zygophyllaceae
Mesh：
Substances：
Year: 2017 PMID： 29177586 DOI： 10.1007/s12272-017-0984-0
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946