Literature DB >> 29177149

Basal Cell Carcinoma in a Childhood Cancer Survivor: What Neurosurgeons Should Avoid.

Zoe Apalla1, Eleni Sotiriou1, Aimilios Lallas1, Elizabeth Lazaridou1, Efstratios Vakirlis1, Demetrios Ioannides1.   

Abstract

Among childhood cancer survivors (CCSs), non-melanoma skin cancer (NMSC) is the most common type of second malignancy. Morbidity related to the development of NMSC in this group of patients may be sometimes unpredictable and difficult to manage. We present the case of a 49-year-old female who was a CCS and developed giant superficial basal cell carcinomas (sBCCs) over the previously irradiated field of the scalp. BCC involved the atrophic skin overlying the catheter of the peritoneal cerebral shunt that was set there for the management of hydrocephalus. Topical treatment with imiquimod 5% resulted in local skin reaction that was further complicated with catheter exposure. The patient underwent an emergency neurosurgery for reposition of the cerebral shunt. Subsequent treatment with imiquimod resulted in complete resolution of sBCC. Given the increased risk for the development of BCCs in CCSs, awareness of neurosurgeons is crucial. Avoidance of setting the catheter of the cerebral shunt within the radiotherapy field is highly recommended, in order to avoid unnecessary future surgeries and subsequent morbidity, as in our case.

Entities:  

Keywords:  Astrocytoma; Basal cell carcinoma; Childhood cancer survivors; Non-melanoma skin cancer; Radiotherapy

Year:  2017        PMID: 29177149      PMCID: PMC5697514          DOI: 10.1159/000476070

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  4 in total

1.  Skin cancer in survivors of childhood and adolescent cancer.

Authors:  Fabio Levi; Raphael Moeckli; Lalao Randimbison; Van-Cong Te; Manuela Maspoli; Carlo La Vecchia
Journal:  Eur J Cancer       Date:  2006-01-26       Impact factor: 9.162

2.  Radiation-related risk of basal cell carcinoma: a report from the Childhood Cancer Survivor Study.

Authors:  Tanya C Watt; Peter D Inskip; Kayla Stratton; Susan A Smith; Stephen F Kry; Alice J Sigurdson; Marilyn Stovall; Wendy Leisenring; Leslie L Robison; Ann C Mertens
Journal:  J Natl Cancer Inst       Date:  2012-07-25       Impact factor: 13.506

3.  Nonmelanoma skin cancer in survivors of childhood and adolescent cancer: a report from the childhood cancer survivor study.

Authors:  Joanna L Perkins; Yan Liu; Pauline A Mitby; Joseph P Neglia; Sue Hammond; Marilyn Stovall; Anna T Meadows; Ray Hutchinson; Zoann E Dreyer; Leslie L Robison; Ann C Mertens
Journal:  J Clin Oncol       Date:  2005-06-01       Impact factor: 50.717

4.  Subsequent neoplasms in 5-year survivors of childhood cancer: the Childhood Cancer Survivor Study.

Authors:  Debra L Friedman; John Whitton; Wendy Leisenring; Ann C Mertens; Sue Hammond; Marilyn Stovall; Sarah S Donaldson; Anna T Meadows; Leslie L Robison; Joseph P Neglia
Journal:  J Natl Cancer Inst       Date:  2010-07-15       Impact factor: 11.816

  4 in total
  1 in total

1.  Secondary basal cell carcinoma of scalp after radiotherapy: A case report.

Authors:  Frank Chen; Sheau-Fang Yang; Chien-Hung Chen; Ann-Shung Lieu; Shih-Tsung Cheng; Ming-Yii Huang; Hsin-Hua Lee
Journal:  Medicine (Baltimore)       Date:  2018-09       Impact factor: 1.817

  1 in total

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