Tian Li1, Xiaoming Feng2, Jianwei Lv3, Tianyao Cai4, Siyou Wang5. 1. Acupuncture Department, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China. 2. The Clinical Research Section, Shanghai Research Institute of Acupuncture and Meridian, Shanghai, China. 3. Department of Urology, Shanghai Jiaotong University School of Medicine Renji Hospital, Shanghai, China. 4. Teaching Section, Shanghai School for the Blind, Shanghai, China. 5. The Clinical Research Section, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine Yueyang Hospital of Traditional Chinese and Western Medicine, Shanghai, China. Electronic address: wangsiyou1234@163.com.
Abstract
OBJECTIVE: To compare the short-term efficacy of electrical pudendal nerve stimulation (EPNS) vs anogenital electrical stimulation (AES) for neurogenic lower urinary tract disease. PATIENTS AND METHODS: Sixty eligible participants were randomized at a ratio of 2:1 to the test group of 40 patients and the control group of 20. The test group was treated with EPNS and the control group was treated with AES. After 12 sessions of treatment, therapeutic effects were evaluated based on self-assessed questionnaire scores. All patients with a residual urine volume >50 mL were also assessed by the post-treatment residual urine volume. RESULTS: At the end of treatment, the median symptom score and the quality of life score were 11 (range 3-23) and 4.26 (range 1.00-5.81) in the test group, and the median post-treatment residual urine volume was 46 (range 0-223) mL. By contrast, the median severity of symptoms and quality of life scores were 15 (range 8-33) and 3.84 (range 0.89-5.84) in the control group, and the median post-treatment residual urine volume was 105 (range 28-340) mL. Significant differences between the test group and the control group could be observed in the post-treatment symptom score, the quality of life score, and the residual urine volume (with P = .005, P <.001, P = .02, respectively). CONCLUSION: Compared with AES, EPNS is more effective in treating neurogenic lower urinary tract disease in the short term.
RCT Entities:
OBJECTIVE: To compare the short-term efficacy of electrical pudendal nerve stimulation (EPNS) vs anogenital electrical stimulation (AES) for neurogenic lower urinary tract disease. PATIENTS AND METHODS: Sixty eligible participants were randomized at a ratio of 2:1 to the test group of 40 patients and the control group of 20. The test group was treated with EPNS and the control group was treated with AES. After 12 sessions of treatment, therapeutic effects were evaluated based on self-assessed questionnaire scores. All patients with a residual urine volume >50 mL were also assessed by the post-treatment residual urine volume. RESULTS: At the end of treatment, the median symptom score and the quality of life score were 11 (range 3-23) and 4.26 (range 1.00-5.81) in the test group, and the median post-treatment residual urine volume was 46 (range 0-223) mL. By contrast, the median severity of symptoms and quality of life scores were 15 (range 8-33) and 3.84 (range 0.89-5.84) in the control group, and the median post-treatment residual urine volume was 105 (range 28-340) mL. Significant differences between the test group and the control group could be observed in the post-treatment symptom score, the quality of life score, and the residual urine volume (with P = .005, P <.001, P = .02, respectively). CONCLUSION: Compared with AES, EPNS is more effective in treating neurogenic lower urinary tract disease in the short term.