| Literature DB >> 29174224 |
Abstract
Parasitic nematodes are biomedically and economically important, but many are genetically intractable which limits our understanding of their molecular and cellular biology. Gang et al. report CRISPR/Cas9 genome editing in parasites of the genus Strongyloides, generating both knock-outs and knock-ins, and demonstrated heritability of the modifications, a crucial advance in the field.Entities:
Keywords: CRISPR; Cas9; Strongyloides; parasitic nematode
Mesh:
Year: 2017 PMID: 29174224 PMCID: PMC5748261 DOI: 10.1016/j.pt.2017.11.005
Source DB: PubMed Journal: Trends Parasitol ISSN: 1471-4922