Avinash Pandey1, Neville Suskin2, Paul Poirier3. 1. Cambridge Cardiac Care Centre, Cambridge, Ontario, Canada; Department of Medicine, Harvard Medical School, Boston, Massachusetts; University of Western Ontario, London, Ontario, Canada. 2. University of Western Ontario, London, Ontario, Canada. 3. Faculty of Pharmacy, Laval University, Québec City, Québec, Canada; Department of Cardiology, Institut de cardiologie et de pneumologie de Québec, Québec City, Québec, Canada. Electronic address: paul.poirier@criucpq.ulaval.ca.
Abstract
BACKGROUND: The impact of burst high-intensity exercise on physiological, cardiometabolic, and biochemical variables compared with traditional moderate-intensity continuous exercise training (MICT) has yet to be assessed in patients with type 2 diabetes (T2D). We compared the impact of multiple short-duration, high-intensity burst exercise sessions to MICT on cardiometabolic variables in patients with T2D. METHODS:Forty newly diagnosed patients with T2D not receiving lipid lowering or hypoglycemic medications were randomized to 40 minutes of MICT (60% of maximal heart rate) 5 days per week or 3 continuous bursts of 12 minutes of high-intensity exercise (85% of maximal heart rate) 5 days per week for 3 months. Body mass index, hemoglobin A1C (HbA1C), and lipid profile were assessed before and after 3 months of exercise training. RESULTS:Burst exercise resulted in greater body mass index reduction than did MICT (-2.1 ± 1.2 kg/m2 vs -0.7 ± 0.7 kg/m2, respectively; P < 0.05). There was a greater reduction at 3 months (P < 0.05) in HbA1C levels in the burst exercise group (8.14% ± 0.49% to 7.32% ± 0.39%) compared with the MICT group (8.18% ± 0.35% to 7.94% ± 0.41%). Compared with MICT, burst exercise was associated with a greater reduction in low-density lipoprotein cholesterol (-11 vs -4%; P < 0.05) and a greater increase in high-density lipoprotein cholesterol (22% vs 3%; all P < 0.05). After 3 months, patients in the burst exercise group attained greater exercise time on the treadmill (exercise capacity) than did those prescribed MICT (6.87 ± 1.44 minutes vs 5.40 ± 1.96 minutes; P < 0.001). CONCLUSIONS: Findings from the current study support better cardiometabolic benefits of burst exercise compared with MICT over 3 months in patients with newly diagnosed T2D.
RCT Entities:
BACKGROUND: The impact of burst high-intensity exercise on physiological, cardiometabolic, and biochemical variables compared with traditional moderate-intensity continuous exercise training (MICT) has yet to be assessed in patients with type 2 diabetes (T2D). We compared the impact of multiple short-duration, high-intensity burst exercise sessions to MICT on cardiometabolic variables in patients with T2D. METHODS: Forty newly diagnosed patients with T2D not receiving lipid lowering or hypoglycemic medications were randomized to 40 minutes of MICT (60% of maximal heart rate) 5 days per week or 3 continuous bursts of 12 minutes of high-intensity exercise (85% of maximal heart rate) 5 days per week for 3 months. Body mass index, hemoglobin A1C (HbA1C), and lipid profile were assessed before and after 3 months of exercise training. RESULTS: Burst exercise resulted in greater body mass index reduction than did MICT (-2.1 ± 1.2 kg/m2 vs -0.7 ± 0.7 kg/m2, respectively; P < 0.05). There was a greater reduction at 3 months (P < 0.05) in HbA1C levels in the burst exercise group (8.14% ± 0.49% to 7.32% ± 0.39%) compared with the MICT group (8.18% ± 0.35% to 7.94% ± 0.41%). Compared with MICT, burst exercise was associated with a greater reduction in low-density lipoprotein cholesterol (-11 vs -4%; P < 0.05) and a greater increase in high-density lipoprotein cholesterol (22% vs 3%; all P < 0.05). After 3 months, patients in the burst exercise group attained greater exercise time on the treadmill (exercise capacity) than did those prescribed MICT (6.87 ± 1.44 minutes vs 5.40 ± 1.96 minutes; P < 0.001). CONCLUSIONS: Findings from the current study support better cardiometabolic benefits of burst exercise compared with MICT over 3 months in patients with newly diagnosed T2D.
Authors: Catherine F S Marriott; Andrea F M Petrella; Emily C S Marriott; Narlon C Boa Sorte Silva; Robert J Petrella Journal: Sports Med Open Date: 2021-07-19
Authors: Rodrigo S Delevatti; Ana Carolina Kanitz; Cristine L Alberton; Elisa Corrêa Marson; Patricia Dias Pantoja; Carolina DertzbocherFeil Pinho; Salime Chedid Lisboa; Luiz Fernando M Kruel Journal: Front Physiol Date: 2018-11-13 Impact factor: 4.566