Literature DB >> 29173400

Channelopathies as Causes of Sudden Cardiac Death.

Peter J Schwartz1, Michael J Ackerman2, Arthur A M Wilde3.   

Abstract

This article reviews the main clinical aspects of 3 channelopathies: the long QT syndrome, the catecholaminergic polymorphic ventricular tachycardia, and the Brugada syndrome. The text summarizes our views on clinical presentation and diagnosis, on risk stratification, and on therapy. Special attention is given to the progress in the understanding of the genetic bases and on the growing impact of genetics on therapy, which, at least in the case of long QT syndrome, now allows gene-specific management.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Brugada syndrome; Catecholaminergic polymorphic ventricular tachycardia; Genetic testing; Ion channels; Left cardiac sympathetic denervation; Long QT syndrome; Ryanodine receptor

Mesh：

Substances：

Year:  2017        PMID： 29173400     DOI： 10.1016/j.ccep.2017.07.005

Source DB:  PubMed          Journal:  Card Electrophysiol Clin        ISSN： 1877-9182


  5 in total

1.  An International Multicenter Evaluation of Type 5 Long QT Syndrome: A Low Penetrant Primary Arrhythmic Condition.

Authors:  Jason D Roberts; S Yukiko Asaki; Andrea Mazzanti; J Martijn Bos; Izabela Tuleta; Alison R Muir; Lia Crotti; Andrew D Krahn; Valentina Kutyifa; M Benjamin Shoemaker; Christopher L Johnsrude; Takeshi Aiba; Luciana Marcondes; Anwar Baban; Sharmila Udupa; Brynn Dechert; Peter Fischbach; Linda M Knight; Eric Vittinghoff; Deni Kukavica; Birgit Stallmeyer; John R Giudicessi; Carla Spazzolini; Keiko Shimamoto; Rafik Tadros; Julia Cadrin-Tourigny; Henry J Duff; Christopher S Simpson; Thomas M Roston; Yanushi D Wijeyeratne; Imane El Hajjaji; Maisoon D Yousif; Lorne J Gula; Peter Leong-Sit; Nikhil Chavali; Andrew P Landstrom; Gregory M Marcus; Sven Dittmann; Arthur A M Wilde; Elijah R Behr; Jacob Tfelt-Hansen; Melvin M Scheinman; Marco V Perez; Juan Pablo Kaski; Robert M Gow; Fabrizio Drago; Peter F Aziz; Dominic J Abrams; Michael H Gollob; Jonathan R Skinner; Wataru Shimizu; Elizabeth S Kaufman; Dan M Roden; Wojciech Zareba; Peter J Schwartz; Eric Schulze-Bahr; Susan P Etheridge; Silvia G Priori; Michael J Ackerman
Journal:  Circulation       Date:  2020-01-16       Impact factor: 29.690

2.  Probing ion channel macromolecular interactions using fluorescence resonance energy transfer.

Authors:  Sharen Rivas; Khadija Hanif; Nourdine Chakouri; Manu Ben-Johny
Journal:  Methods Enzymol       Date:  2021-03-15       Impact factor: 1.600

3.  TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines.

Authors:  Rocio Cikutović-Molina; Andres A Herrada; Wendy González; Nelson Brown; Leandro Zúñiga
Journal:  Int J Mol Sci       Date:  2019-12-02       Impact factor: 5.923

4.  Exploring mutation specific beta blocker pharmacology of the pathogenic late sodium channel current from patient-specific pluripotent stem cell myocytes derived from long QT syndrome mutation carriers.

Authors:  Thomas W Comollo; Xinle Zou; Chuangeng Zhang; Divya Kesters; Thomas Hof; Kevin J Sampson; Robert S Kass
Journal:  Channels (Austin)       Date:  2022-12       Impact factor: 3.493

5.  Polyunsaturated fatty acids produce a range of activators for heterogeneous IKs channel dysfunction.

Authors:  Briana M Bohannon; Xiaoan Wu; Xiongyu Wu; Marta E Perez; Sara I Liin; H Peter Larsson
Journal:  J Gen Physiol       Date:  2020-02-03       Impact factor: 4.086
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.