Literature DB >> 29171665

Bypassing the barrier: new routes for delivery of macromolecules to the central nervous system.

Shane Liddelow1.   

Abstract

Keywords:  antibody; blood-brain barrier; cerebral blood flow; cerebrospinal fluid; drug delivery; glymphatics

Mesh:

Substances:

Year:  2017        PMID: 29171665      PMCID: PMC5792525          DOI: 10.1113/JP275499

Source DB:  PubMed          Journal:  J Physiol        ISSN: 0022-3751            Impact factor:   5.182


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2.  A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

Authors:  Jeffrey J Iliff; Minghuan Wang; Yonghong Liao; Benjamin A Plogg; Weiguo Peng; Georg A Gundersen; Helene Benveniste; G Edward Vates; Rashid Deane; Steven A Goldman; Erlend A Nagelhus; Maiken Nedergaard
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3.  Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery.

Authors:  Michelle E Pizzo; Daniel J Wolak; Niyanta N Kumar; Eric Brunette; Christina L Brunnquell; Melanie-Jane Hannocks; N Joan Abbott; M Elizabeth Meyerand; Lydia Sorokin; Danica B Stanimirovic; Robert G Thorne
Journal:  J Physiol       Date:  2017-12-18       Impact factor: 5.182

Review 4.  The biological significance of brain barrier mechanisms: help or hindrance in drug delivery to the central nervous system?

Authors:  Norman R Saunders; Mark D Habgood; Kjeld Møllgård; Katarzyna M Dziegielewska
Journal:  F1000Res       Date:  2016-03-10
  4 in total
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1.  Shedding Light on the Blood-Brain Barrier Transport with Two-Photon Microscopy In Vivo.

Authors:  Krzysztof Kucharz; Nikolay Kutuzov; Oleg Zhukov; Mette Mathiesen Janiurek; Martin Lauritzen
Journal:  Pharm Res       Date:  2022-05-16       Impact factor: 4.200

  1 in total

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