Literature DB >> 29171078

Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross-sectional study of 500 000 UK Biobank participants.

L D Ferguson1, U E Ntuk2, C Celis-Morales1, D F Mackay2, J P Pell2, J M R Gill1, N Sattar1.   

Abstract

AIMS: Studies show that white men have a higher prevalence of Type 2 diabetes mellitus than women at a given age and BMI, but equivalent standardized data for other ethnic groups in the UK are sparse.
METHODS: This cross-sectional study analysed UK Biobank data from 489 079 participants to compare the prevalence of diabetes mellitus across four major ethnic groups including: 471 700 (96.4%) white, 7871 (1.6%) South Asian, 7974 (1.6%) black and 1534 (0.3%) Chinese participants, before and after standardizing for age, socio-economic status (SES), BMI and lifestyle factors including physical activity, TV viewing, fruit and vegetable intake, processed meat, red meat, oily fish, alcohol intake and smoking. A subgroup analysis of South Asians was also undertaken.
RESULTS: Crude diabetes prevalence was higher in men across all four ethnicities. After standardizing for age, SES, BMI and lifestyle factors, a significant sex difference in diabetes prevalence persisted in white (men 6.0% vs. women 3.6%), South Asian (21.0% vs. 13.8%) and black individuals (13.3% vs. 9.7%) (P < 0.0001); there was a non-significant difference between Chinese men and women (7.1% vs. 5.5%) (P = 0.211). Sex differences persisted across South Asian subgroups.
CONCLUSIONS: Men across a range of major ethnic groups including white, South Asian and black, have a higher prevalence of diabetes compared with women of similar age, BMI, SES and lifestyle in the UK.
© 2017 Diabetes UK.

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Mesh:

Year:  2017        PMID: 29171078     DOI: 10.1111/dme.13551

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  5 in total

Review 1.  Sex differences in the burden of type 2 diabetes and cardiovascular risk across the life course.

Authors:  Amy G Huebschmann; Rachel R Huxley; Wendy M Kohrt; Philip Zeitler; Judith G Regensteiner; Jane E B Reusch
Journal:  Diabetologia       Date:  2019-08-27       Impact factor: 10.122

2.  Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes: A prospective cohort study in the UK Biobank.

Authors:  Frederick K Ho; Lyn D Ferguson; Carlos A Celis-Morales; Stuart R Gray; Ewan Forrest; William Alazawi; Jason Mr Gill; Srinivasa Vittal Katikireddi; John Gf Cleland; Paul Welsh; Jill P Pell; Naveed Sattar
Journal:  EClinicalMedicine       Date:  2022-05-12

3.  Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study.

Authors:  Jason Martin Regnald Gill; Naveed Sattar; Carlos Celis-Morales; Mirthe Muilwijk; Frederick Ho; Heather Waddell; Anne Sillars; Paul Welsh; Stamatina Iliodromiti; Rosemary Brown; Lyn Ferguson; Karien Stronks; Irene van Valkengoed; Jill P Pell; Stuart Robert Gray
Journal:  BMJ Open Diabetes Res Care       Date:  2019-12-17

4.  Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening.

Authors:  Jana J Anderson; Paul Welsh; Frederick K Ho; Lyn D Ferguson; Claire E Welsh; Pierpaolo Pellicori; John G F Cleland; John Forbes; Stamatina Iliodromiti; James Boyle; Robert Lindsay; Carlos Celis-Morales; Stuart Robert Gray; Srinivasa Vittal Katikireddi; Jason Martin Regnald Gill; Jill P Pell; Naveed Sattar
Journal:  BMJ Open Diabetes Res Care       Date:  2021-08

5.  Associations between grip strength and incident type 2 diabetes: findings from the UK Biobank prospective cohort study.

Authors:  Frederick K Ho; Stuart Robert Gray; Carlos Celis-Morales; Jirapitcha Boonpor; Solange Parra-Soto; Fanny Petermann-Rocha; Gerson Ferrari; Paul Welsh; Jill P Pell; Naveed Sattar; Jason Martin Regnald Gill
Journal:  BMJ Open Diabetes Res Care       Date:  2021-08
  5 in total

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