Literature DB >> 2917103

Fatal haemopathological consequences of general anaesthesia.

P J Wright1, J R Shortland, J D Stevens, M A Parsons, J Watkins.   

Abstract

A previously healthy 63-yr-old female died following an anaphylactoid response to anaesthesia with thiopentone and suxamethonium. Postmortem findings strongly suggested that disseminated intravascular coagulation played a significant role in her death. The local mechanism behind the reaction is unknown, but the formation of thiopentone-suxamethonium colloid aggregates during induction, may have led to "aggregate anaphylaxis".

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Year:  1989        PMID: 2917103     DOI: 10.1093/bja/62.1.104

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  2 in total

1.  Problems of mediator measurement for a national advisory service to U.K. anaesthetists.

Authors:  J Watkins; G Wild
Journal:  Agents Actions       Date:  1990-04

Review 2.  Allergy to thiopentone.

Authors:  B A Baldo; M M Fisher; D G Harle
Journal:  Clin Rev Allergy       Date:  1991 Fall-Winter
  2 in total

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