| Literature DB >> 29170182 |
Rohan Chawla1, Koushik Tripathy1.
Abstract
We report two patients with chronic myelogenous leukaemia (CML) in remission phase who developed panuveitis simulating Behçet's disease. A 26-year-old man presented with bilateral panuveitis (hypopyon in the right eye, bilateral anterior segment inflammation, vitritis and retinitis). He was on imatinib for CML which was in remission. He gave a history of recurrent oral ulcers. The panuveitis responded to oral and topical steroids but recurred after the steroids were stopped. His ocular condition again stabilised on restarting oral steroids and azathioprine. The second patient, a 28-year-old man, presented with bilateral anterior segment inflammation, vitritis, exudative retinal detachment and hypopyon in the right eye. He was also on imatinib with the CML being in remission. The uveitis and exudative retinal detachment improved on systemic and topical steroids. The vision of this patient did not improve as optic atrophy ensued. The panuveitis seen in our patients with CML responded favourably to oral steroids/immunosuppressant therapy. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.Entities:
Keywords: ophthalmology; retina
Mesh:
Substances:
Year: 2017 PMID: 29170182 PMCID: PMC5720255 DOI: 10.1136/bcr-2017-222238
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X