Literature DB >> 29170182

Panuveitis simulating ocular Behçet's in cases of chronic myelogenous leukaemia in remission.

Rohan Chawla1, Koushik Tripathy1.   

Abstract

We report two patients with chronic myelogenous leukaemia (CML) in remission phase who developed panuveitis simulating Behçet's disease. A 26-year-old man presented with bilateral panuveitis (hypopyon in the right eye, bilateral anterior segment inflammation, vitritis and retinitis). He was on imatinib for CML which was in remission. He gave a history of recurrent oral ulcers. The panuveitis responded to oral and topical steroids but recurred after the steroids were stopped. His ocular condition again stabilised on restarting oral steroids and azathioprine. The second patient, a 28-year-old man, presented with bilateral anterior segment inflammation, vitritis, exudative retinal detachment and hypopyon in the right eye. He was also on imatinib with the CML being in remission. The uveitis and exudative retinal detachment improved on systemic and topical steroids. The vision of this patient did not improve as optic atrophy ensued. The panuveitis seen in our patients with CML responded favourably to oral steroids/immunosuppressant therapy. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  ophthalmology; retina

Mesh:

Substances:

Year:  2017        PMID: 29170182      PMCID: PMC5720255          DOI: 10.1136/bcr-2017-222238

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

1.  Neutrophilic phlebitis is characteristic of intestinal Behçet's disease and simple ulcer syndrome.

Authors:  N Hayasaki; M Ito; T Suzuki; K Ina; T Ando; K Kusugami; H Goto
Journal:  Histopathology       Date:  2004-10       Impact factor: 5.087

2.  Treatment of colitis in Behçet's disease with thalidomide.

Authors:  P T Postema; P den Haan; P M van Hagen; M van Blankenstein
Journal:  Eur J Gastroenterol Hepatol       Date:  1996-09       Impact factor: 2.566

Review 3.  New insights into the pathogenesis of Behçet's disease.

Authors:  Marc Pineton de Chambrun; Bertrand Wechsler; Guillaume Geri; Patrice Cacoub; David Saadoun
Journal:  Autoimmun Rev       Date:  2011-12-11       Impact factor: 9.754

4.  Behcet's disease in a patient with chronic myelogenous leukemia under hydroxyurea treatment: a case report and review of the literature.

Authors:  G Vaiopoulos; E Terpos; N Viniou; K Nodaros; J Rombos; D Loukopoulos
Journal:  Am J Hematol       Date:  2001-01       Impact factor: 10.047

5.  Serial ultra wide field imaging for following up acute retinal necrosis cases.

Authors:  Koushik Tripathy; Yog Raj Sharma; Varun Gogia; Pradeep Venkatesh; Subodh Kumar Singh; Rajpal Vohra
Journal:  Oman J Ophthalmol       Date:  2015 Jan-Apr

6.  Periarterial Plaques (Kyrieleis' Arteriolitis) in a Case of Bilateral Acute Retinal Necrosis.

Authors:  Rohan Chawla; Koushik Tripathy; Yog Raj Sharma; Pradeep Venkatesh; Rajpal Vohra
Journal:  Semin Ophthalmol       Date:  2015-07-10       Impact factor: 1.975

7.  Neutrophil and endothelial cell activation in the vasa vasorum in vasculo-Behçet disease.

Authors:  M Kobayashi; M Ito; A Nakagawa; M Matsushita; N Nishikimi; T Sakurai; Y Nimura
Journal:  Histopathology       Date:  2000-04       Impact factor: 5.087

Review 8.  Development of large genital ulcer due to hydroxyurea treatment in a patient with chronic myeloid leukemia and Behcet's disease.

Authors:  Yelda Karincaoglu; Emin Kaya; Muammer Esrefoglu; Ismet Aydogdu
Journal:  Leuk Lymphoma       Date:  2003-06

9.  Behçet's disease induced by interferon therapy for chronic myelogenous leukemia.

Authors:  F Segawa; Y Shimizu; E Saito; M Kinoshita
Journal:  J Rheumatol       Date:  1995-06       Impact factor: 4.666

10.  Excessive function of peripheral blood neutrophils from patients with Behçet's disease and from HLA-B51 transgenic mice.

Authors:  M Takeno; A Kariyone; N Yamashita; M Takiguchi; Y Mizushima; H Kaneoka; T Sakane
Journal:  Arthritis Rheum       Date:  1995-03
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