| Literature DB >> 29168067 |
Ali Mirzazadeh1, Jennifer L Evans2, Judith A Hahn2,3, Jennifer Jain4, Alya Briceno2, Stephen Shiboski5, Paula J Lum3, Christopher Bentsen6, Geoff Davis6, Kathy Shriver6, Melanie Dimapasoc7, Mars Stone7, Michael P Busch7,8, Kimberly Page9.
Abstract
We measured HIV incidence rate, trend and risk factors in 564 HIV-negative young people (< 30 years) who inject drugs (PWID) in San Francisco between 2000 and 2014. HIV incidence was 0.93/100 person-years (PY; 95% CI 0.50, 1.73). Incidence varied between 0.62/100 PY in 2000-2002 and 1.06/100 PY in 2012-2014 (P for trend = 1.0). HIV incidence varied significantly (P < 0.01) by race/ethnicity: among Hispanics it was 8.19/100 PY (95% CI 3.41, 19.68), African-Americans 4.59/100 PY (95% CI 1.15, 18.37), and Whites 0.26/100 PY (95% CI 0.06, 1.03). Male participants who reported sex with men (MSM) had higher HIV incidence (2.63/100 PY; 95% CI 1.31, 5.25) compared to males who did not report MSM (0.50/100 PY; 95% CI 0.12, 1.99) (P = 0.01). Despite an overall stable HIV incidence trend, incidence was elevated among African-American and Hispanic PWID, and men who have sex with men. Addressing prevention needs in these key populations is critical for the goal of eliminating HIV transmission.Entities:
Keywords: Cohort studies; Drug users; Epidemiology; HIV; Incidence; Injection; San Francisco; Young adults
Mesh:
Year: 2018 PMID: 29168067 PMCID: PMC6054135 DOI: 10.1007/s10461-017-1988-y
Source DB: PubMed Journal: AIDS Behav ISSN: 1090-7165