Di Liang1, Jingyi Zhang1, Li Lin1, Wenxia Zong1. 1. Department of Cardiology, The Third People's Hospital of Hubei Province, Wuhan, Hubei 430033, China.
Abstract
OBJECTIVES: To investigate whether the fragmented QRS (fQRS) complexes can be used to distinguish patients with early non-ST elevation myocardial infarction (NSTEMI) from those with unstable angina (UA). BACKGROUND: fQRS complex has been found to be linked to myocardial infarction and cardiac death. METHODS: The clinical data of 302 patients who had been diagnosed with coronary artery disease were retrospectively reviewed. Incidence of fQRS complex within 48 h of presentation was analyzed and patients with acute myocardial infarction (AMI) (n = 240) were followed up by telephone interviews for a mean of 61.47 (range, 59.60-63.35) months. RESULTS: Patients with NSTEMI exhibited higher incidence of fQRS than those with UA (p = 0.047). The incidence of fQRS in the inferior wall leads was significantly higher than that of other leads in patients with anterior wall infarction (p < 0.05). Kaplan-Meier analysis revealed a higher mortality rate in AMI patients with fQRS compared to non-fQRS patients (p = 0.001). CONCLUSIONS: Presence of fQRS complexes within 48 hours of presentation may be used to differentiate NSTEMI patients from UA patients. fQRS may also be used as a survival predictor for patients with AMI.
OBJECTIVES: To investigate whether the fragmented QRS (fQRS) complexes can be used to distinguish patients with early non-ST elevation myocardial infarction (NSTEMI) from those with unstable angina (UA). BACKGROUND: fQRS complex has been found to be linked to myocardial infarction and cardiac death. METHODS: The clinical data of 302 patients who had been diagnosed with coronary artery disease were retrospectively reviewed. Incidence of fQRS complex within 48 h of presentation was analyzed and patients with acute myocardial infarction (AMI) (n = 240) were followed up by telephone interviews for a mean of 61.47 (range, 59.60-63.35) months. RESULTS: Patients with NSTEMI exhibited higher incidence of fQRS than those with UA (p = 0.047). The incidence of fQRS in the inferior wall leads was significantly higher than that of other leads in patients with anterior wall infarction (p < 0.05). Kaplan-Meier analysis revealed a higher mortality rate in AMI patients with fQRS compared to non-fQRS patients (p = 0.001). CONCLUSIONS: Presence of fQRS complexes within 48 hours of presentation may be used to differentiate NSTEMI patients from UA patients. fQRS may also be used as a survival predictor for patients with AMI.
Authors: Mithilesh Kumar Das; Chandan Saha; Hicham El Masry; Jonathan Peng; Gopi Dandamudi; Jo Mahenthiran; Paul McHenry; Douglas P Zipes Journal: Heart Rhythm Date: 2007-08-01 Impact factor: 6.343
Authors: Andrew Brenyo; Grzegorz Pietrasik; Alon Barsheshet; David T Huang; Bronislava Polonsky; Scott McNitt; Arthur J Moss; Wojciech Zareba Journal: J Cardiovasc Electrophysiol Date: 2012-07-16
Authors: N C Flowers; L G Horan; A C Wylds; W Crawford; M R Sridharan; C P Horan; S F Cliff Journal: Am J Cardiol Date: 1990-09-01 Impact factor: 2.778
Authors: Mithilesh K Das; Mark A Michael; Hussam Suradi; Jonathan Peng; Anjan Sinha; Changyu Shen; Jo Mahenthiran; Richard J Kovacs Journal: Am J Cardiol Date: 2009-12-15 Impact factor: 2.778
Authors: Azam Torabi; John G F Cleland; Nasrin K Khan; Puan H Loh; Andrew L Clark; Farqad Alamgir; John L Caplin; Alan S Rigby; Kevin Goode Journal: Eur Heart J Date: 2008-03-19 Impact factor: 29.983
Authors: Grzegorz Pietrasik; Ilan Goldenberg; Joanna Zdzienicka; Arthur J Moss; Wojciech Zareba Journal: Am J Cardiol Date: 2007-06-29 Impact factor: 2.778
Authors: Osman Bektaş; Ahmet Karagöz; Adil Bayramoğlu; Erdal Benli; Zeki Yüksel Günaydın; Mehmet Yaman; Ahmet Kaya Journal: Acta Cardiol Sin Date: 2018-11 Impact factor: 2.672