| Literature DB >> 29167218 |
Robert Maweni1, Jins Kallampallil1, Szewai Leong2, Srikanth Akunuri1.
Abstract
We describe the case of a 50-year-old woman presenting to our acute medicine department with generalised non-specific symptoms on a background of HIV managed on triple therapy (tenofovir, lamivudine and zidovudine). On admission, she was noted to be acidotic with proteinuria, glycosuria, hypophosphataemia and generalised body pain, and was diagnosed with Fanconi's renotubular syndrome secondary to tenofovir. It was also noted that she had elevated liver dysfunction markers, and an MRI of the liver revealed a focal stricture near the ampulla of Vater, resulting in a diagnosis of AIDS cholangiopathy. These two diagnoses are rare complications of HIV, and the presence of both these pathologies in a single patient has never been reported in the literature before, and we therefore believe that this case is the first of its kind. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.Entities:
Keywords: hiv / aids; unwanted effects / adverse reactions
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Year: 2017 PMID: 29167218 PMCID: PMC5720260 DOI: 10.1136/bcr-2017-222333
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X