Literature DB >> 29166322

Biological/Genetic Regulation of Physical Activity Level: Consensus from GenBioPAC.

J Timothy Lightfoot1,1, Eco J C DE Geus1,1, Frank W Booth1,1, Molly S Bray1,1, Marcel DEN Hoed1,1, Jaakko Kaprio1,1, Scott A Kelly1,1, Daniel Pomp1,1, Michael C Saul1,1, Martine A Thomis1,1, Theodore Garland1,1, Claude Bouchard1,1.   

Abstract

PURPOSE: Physical activity unquestionably maintains and improves health; however, physical activity levels globally are low and not rising despite all the resources devoted to this goal. Attention in both the research literature and the public policy domain has focused on social-behavioral factors; however, a growing body of literature suggests that biological determinants play a significant role in regulating physical activity levels. For instance, physical activity level, measured in various manners, has a genetic component in both humans and nonhuman animal models. This consensus article, developed as a result of an American College of Sports Medicine-sponsored round table, provides a brief review of the theoretical concepts and existing literature that supports a significant role of genetic and other biological factors in the regulation of physical activity.
CONCLUSIONS: Future research on physical activity regulation should incorporate genetics and other biological determinants of physical activity instead of a sole reliance on social and other environmental determinants.

Entities:  

Mesh:

Year:  2018        PMID: 29166322      PMCID: PMC6481631          DOI: 10.1249/MSS.0000000000001499

Source DB:  PubMed          Journal:  Med Sci Sports Exerc        ISSN: 0195-9131            Impact factor:   5.411


  20 in total

1.  Chronic diseases and objectively monitored physical activity profile among aged individuals - a cross-sectional twin cohort study.

Authors:  Urho M Kujala; Pekka Hautasaari; Henri Vähä-Ypyä; Katja Waller; Noora Lindgren; Paula Iso-Markku; Kauko Heikkilä; Juha Rinne; Jaakko Kaprio; Harri Sievänen
Journal:  Ann Med       Date:  2019-03-05       Impact factor: 4.709

2.  Reply to Williams et al.: Comment on: "Equity in Physical Activity: A Misguided Goal".

Authors:  James L Nuzzo
Journal:  Sports Med       Date:  2019-04       Impact factor: 11.136

3.  Relationship between gene expression networks and muscle contractile physiology differences in Anolis lizards.

Authors:  Luke B Smith; Christopher V Anderson; Miyuraj H Hikkaduwa Withangage; Andrew Koch; Thomas J Roberts; Andrea L Liebl
Journal:  J Comp Physiol B       Date:  2022-05-20       Impact factor: 2.230

4.  Mechanisms of Exercise-Induced Cardiac Remodeling Differ Between Young and Aged Hearts.

Authors:  Emily E Schmitt; Benjamin D McNair; Sydney M Polson; Ross F Cook; Danielle R Bruns
Journal:  Exerc Sport Sci Rev       Date:  2022-05-05       Impact factor: 6.642

5.  Genetic Basis of Aerobically Supported Voluntary Exercise: Results from a Selection Experiment with House Mice.

Authors:  David A Hillis; Liran Yadgary; George M Weinstock; Fernando Pardo-Manuel de Villena; Daniel Pomp; Alexandra S Fowler; Shizhong Xu; Frank Chan; Theodore Garland
Journal:  Genetics       Date:  2020-09-25       Impact factor: 4.562

6.  Effects of early-life exposure to Western diet and voluntary exercise on adult activity levels, exercise physiology, and associated traits in selectively bred High Runner mice.

Authors:  Marcell D Cadney; Layla Hiramatsu; Zoe Thompson; Meng Zhao; Jarren C Kay; Jennifer M Singleton; Ralph Lacerda de Albuquerque; Margaret P Schmill; Wendy Saltzman; Theodore Garland
Journal:  Physiol Behav       Date:  2021-03-16

7.  Physical Activity and Academic Performance: Genetic and Environmental Associations.

Authors:  Sari Aaltonen; Antti Latvala; Aline Jelenkovic; Richard J Rose; Urho M Kujala; Jaakko Kaprio; Karri Silventoinen
Journal:  Med Sci Sports Exerc       Date:  2020-02

8.  Genome-wide association studies of 27 accelerometry-derived physical activity measurements identified novel loci and genetic mechanisms.

Authors:  Guanghao Qi; Diptavo Dutta; Andrew Leroux; Debashree Ray; John Muschelli; Ciprian Crainiceanu; Nilanjan Chatterjee
Journal:  Genet Epidemiol       Date:  2022-01-18       Impact factor: 2.344

9.  Brain region-dependent gene networks associated with selective breeding for increased voluntary wheel-running behavior.

Authors:  Pan Zhang; Justin S Rhodes; Theodore Garland; Sam D Perez; Bruce R Southey; Sandra L Rodriguez-Zas
Journal:  PLoS One       Date:  2018-08-02       Impact factor: 3.240

10.  Genomewide Association Study of Leisure-Time Exercise Behavior in Japanese Adults.

Authors:  Megumi Hara; Tsuyoshi Hachiya; Yoichi Sutoh; Keitaro Matsuo; Yuichiro Nishida; Chisato Shimanoe; Keitaro Tanaka; Atsushi Shimizu; Keizo Ohnaka; Takahisa Kawaguchi; Isao Oze; Fumihiko Matsuda; Hidemi Ito; Sayo Kawai; Asahi Hishida; Rieko Okada; Tae Sasakabe; Akie Hirata; Rie Ibusuki; Yora Nindita; Norihiro Furusyo; Hiroaki Ikezaki; Nagato Kuriyama; Etsuko Ozaki; Haruo Mikami; Yohko Nakamura; Sadao Suzuki; Akihiro Hosono; Sakurako Katsuura-Kamano; Kokichi Arisawa; Kiyonori Kuriki; Kaori Endoh; Naoyuki Takashima; Aya Kadota; Masahiro Nakatochi; Yukihide Momozawa; Michiaki Kubo; Mariko Naito; Kenji Wakai
Journal:  Med Sci Sports Exerc       Date:  2018-12       Impact factor: 5.411

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