A Garros1, S Marjoux1, C Khouatra2, B Coppere3, C Grange4, A Hot3, S Roman1, H Damon1, F Mion1. 1. Hospices Civils de Lyon, Hospital Edouard Herriot, Digestive Physiology, Lyon I University, and INSERM 1032 LabTAU, Lyon, France. 2. Hospices Civils de Lyon, Hospital Louis Pradel, Pneumology, Bron, France. 3. Hospices Civils de Lyon, Hospital Edouard Herriot, Internal Medicine, Lyon, France. 4. Hospices Civils de Lyon, Hospital Jules Courmont, Internal Medicine, Lyon, France.
Abstract
BACKGROUND: The prevalence of gastrointestinal involvement in systemic sclerosis is higher than 75%. The estimated prevalence of fecal incontinence varies from 22% to 77%, but suffers from recruitment bias and patient reluctance. Our goal was to evaluate the prevalence of fecal incontinence in systemic sclerosis, and to identify associated risk factors. METHODS: Patients were recruited in the referral systemic sclerosis network of the Lyon University Hospitals, using self-administered questionnaires including constipation, fecal incontinence and Bristol Stool scales, quality of life, anxiety and depression. The cohort was compared with the historical ORALIA cohort that established the prevalence of fecal incontinence in the general population of the Rhône-Alpes region (France). RESULTS: Seventy-seven patients were included (mean age: 60 years, range: 32-84), and 86% were female. These were compared to 153 ORALIA individuals matched for age and sex. Fecal incontinence was present in 38% of patients and 6% of the general population. A longer duration of systemic sclerosis was the only characteristic associated with fecal incontinence. Abnormal stool consistency was more frequent in patients with fecal incontinence. CONCLUSION: Fecal incontinence and abnormal stool consistency are common in systemic sclerosis and should be systematically addressed.
BACKGROUND: The prevalence of gastrointestinal involvement in systemic sclerosis is higher than 75%. The estimated prevalence of fecal incontinence varies from 22% to 77%, but suffers from recruitment bias and patient reluctance. Our goal was to evaluate the prevalence of fecal incontinence in systemic sclerosis, and to identify associated risk factors. METHODS: Patients were recruited in the referral systemic sclerosis network of the Lyon University Hospitals, using self-administered questionnaires including constipation, fecal incontinence and Bristol Stool scales, quality of life, anxiety and depression. The cohort was compared with the historical ORALIA cohort that established the prevalence of fecal incontinence in the general population of the Rhône-Alpes region (France). RESULTS: Seventy-seven patients were included (mean age: 60 years, range: 32-84), and 86% were female. These were compared to 153 ORALIA individuals matched for age and sex. Fecal incontinence was present in 38% of patients and 6% of the general population. A longer duration of systemic sclerosis was the only characteristic associated with fecal incontinence. Abnormal stool consistency was more frequent in patients with fecal incontinence. CONCLUSION: Fecal incontinence and abnormal stool consistency are common in systemic sclerosis and should be systematically addressed.
Entities:
Keywords:
Systemic sclerosis; constipation; fecal incontinence; quality of life
Authors: Sarah B Umar; Leroy Griffing; Heidi Garcia; Amy E Foxx-Orenstein; John K DiBaise; Michael D Crowell Journal: J Clin Gastroenterol Date: 2016-07 Impact factor: 3.062
Authors: Henri Damon; Anne Marie Schott; Xavier Barth; Jean Luc Faucheron; Laurent Abramowitz; Laurent Siproudhis; Marie-Odile Fayard; Cyrille Colin; Guy Valancogne; Véronique Bonniaud; François Mion Journal: Int J Colorectal Dis Date: 2008-05-28 Impact factor: 2.571