Literature DB >> 29159733

Management of Hemophilia in Older Patients.

Massimo Franchini1, Pier Mannuccio Mannucci2.   

Abstract

In recent decades, several improvements in hemophilia care have resulted in increased quality of life and life expectancy for those affected by this inherited hemorrhagic condition. Nowadays, individuals with hemophilia enjoy a life expectancy at birth close to that of males in the general population. As a consequence of the increasing age of the hemophilia population, a growing number of these patients develop age-related co-morbidities, such as cardiovascular disease and cancer, the management of which represents a new challenge for caregivers at hemophilia treatment centers. This narrative review focuses on the clinical problems arising in older people with hemophilia, with particular attention to the optimal therapeutic strategies.

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Year:  2017        PMID: 29159733     DOI: 10.1007/s40266-017-0500-8

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  100 in total

1.  Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis.

Authors:  G C White; F Rosendaal; L M Aledort; J M Lusher; C Rothschild; J Ingerslev
Journal:  Thromb Haemost       Date:  2001-03       Impact factor: 5.249

2.  Coronary artery calcification score and carotid intima–media thickness in patients with hemophilia.

Authors:  Marjan Zwiers; J D Lefrandt; D J Mulder; A J Smit; R O B Gans; R Vliegenthart; A V M Brands-Nijenhuis; J C Kluin-Nelemans; K Meijer
Journal:  J Thromb Haemost       Date:  2012-01       Impact factor: 5.824

Review 3.  Thrombin and cancer: from molecular basis to therapeutic implications.

Authors:  Massimo Franchini; Pier Mannuccio Mannucci
Journal:  Semin Thromb Hemost       Date:  2012-02-07       Impact factor: 4.180

Review 4.  Half-life extension technologies for haemostatic agents.

Authors:  Pier Mannuccio Mannucci
Journal:  Thromb Haemost       Date:  2014-10-02       Impact factor: 5.249

Review 5.  Progress in the contemporary management of hemophilia: The new issue of patient aging.

Authors:  Pier Mannuccio Mannucci; Massimo Iacobelli
Journal:  Eur J Intern Med       Date:  2017-05-20       Impact factor: 4.487

6.  Mortality and causes of death in Italian persons with haemophilia, 1990-2007.

Authors:  A Tagliaferri; G F Rivolta; A Iorio; E Oliovecchio; M E Mancuso; M Morfini; A Rocino; M G Mazzucconi; M Franchini; N Ciavarella; A Scaraggi; L Valdrè; G Tagariello; P Radossi; G Muleo; P G Iannaccaro; C Biasoli; D Vincenzi; M L Serino; S Linari; C Molinari; E Boeri; M La Pecorella; M T Carloni; E Santagostino; G Di Minno; A Coppola; A Rocino; E Zanon; L Spiezia; C Di Perna; M Marchesini; M Marcucci; A Dragani; S Macchi; P Albertini; M D'Incà; C Santoro; F Biondo; G Piseddu; G Rossetti; G Barillari; G Gandini; A C Giuffrida; G Castaman
Journal:  Haemophilia       Date:  2010-02-09       Impact factor: 4.287

Review 7.  Clinical management of older persons with haemophilia.

Authors:  C Hermans; P de Moerloose; G Dolan
Journal:  Crit Rev Oncol Hematol       Date:  2013-08-13       Impact factor: 6.312

8.  Physical condition, longevity, and social performance of Dutch haemophiliacs, 1972-85.

Authors:  C Smit; F R Rosendaal; I Varekamp; A Bröcker-Vriends; H Van Dijck; T P Suurmeijer; E Briët
Journal:  BMJ       Date:  1989-01-28

Review 9.  Hemophilia and cancer: a new challenge for hemophilia centers.

Authors:  Massimo Franchini; Giuseppe Lippi; Martina Montagnana; Giovanni Targher; Marco Zaffanello; Gian Luca Salvagno; Gianna Franca Rivolta; Caterina Di Perna; Annarita Tagliaferri
Journal:  Cancer Treat Rev       Date:  2009-02-04       Impact factor: 12.111

Review 10.  Outcome of Clinical Trials with New Extended Half-Life FVIII/IX Concentrates.

Authors:  Maria Elisa Mancuso; Elena Santagostino
Journal:  J Clin Med       Date:  2017-03-28       Impact factor: 4.241

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  1 in total

1.  Analysis of Sasang Constitutional Medicine as an Optimal Preventive Care Strategy for Hemophilia Patients.

Authors:  Mi Kyung Lee; Minwoo Hwang; Hyunjoo Oh; Kyoung Soo Kim
Journal:  Biomed Res Int       Date:  2020-02-01       Impact factor: 3.411

  1 in total

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