Literature DB >> 2915803

A case of Alzheimer's disease and hippocampal sclerosis with normal cholinergic activity in basal forebrain, neocortex, and hippocampus.

R M Zweig1, K M Schegg, J H Peacock, D Melarkey.   

Abstract

A 76-year-old man without apparent dementia met pathologic criteria at autopsy for Alzheimer's disease, which included a maximum senile plaque density greater than 15 per square millimeter of neocortex. Despite hippocampal sclerosis, changes typical of Alzheimer's disease were not found in this region or in basal forebrain. Choline acetyltransferase activity in hippocampus, septum, and parietal cortex was normal.

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Year:  1989        PMID： 2915803     DOI： 10.1212/wnl.39.2.288

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  4 in total

1.  A 10-year experience with 290 pancreas transplants at a single institution.

Authors:  D E Sutherland; D L Dunn; F C Goetz; W Kennedy; R C Ramsay; M W Steffes; S M Mauer; R Gruessner; K C Moudry-Munns; P Morel
Journal:  Ann Surg       Date:  1989-09       Impact factor: 12.969

2.  Hippocampal sclerosis: a common pathological feature of dementia in very old (> or = 80 years of age) humans.

Authors:  D W Dickson; P Davies; C Bevona; K H Van Hoeven; S M Factor; E Grober; M K Aronson; H A Crystal
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

3.  Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration.

Authors:  Catalina Amador-Ortiz; Zeshan Ahmed; Cynthia Zehr; Dennis W Dickson
Journal:  Acta Neuropathol       Date:  2006-12-30       Impact factor: 17.088

4.  Advances in Deep Neuropathological Phenotyping of Alzheimer Disease: Past, Present, and Future.

Authors:  Mustafa N Shakir; Brittany N Dugger
Journal:  J Neuropathol Exp Neurol       Date:  2022-01-21       Impact factor: 3.685
  4 in total

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