| Literature DB >> 29157908 |
Khalid Mahmood Zia1, Shazia Tabasum2, Muhammad Faris Khan3, Nadia Akram2, Naheed Akhter4, Aqdas Noreen2, Mohammad Zuber2.
Abstract
Gellan gum (GG), a linear negatively charged exopolysaccharide,is biodegradable and non-toxic in nature. It produces hard and translucent gel in the presence of metallic ions which is stable at low pH. However, GG has poor mechanical strength, poor stability in physiological conditions, high gelling temperature and small temperature window.Therefore,it is blended with different polymers such as agar, chitosan, cellulose, sodium alginate, starch, pectin, polyanaline, pullulan, polyvinyl chloride, and xanthan gum. In this article, a comprehensive overview of combination of GG with natural and synthetic polymers/compounds and their applications in biomedical field involving drug delivery system, insulin delivery, wound healing and gene therapy, is presented. It also describes the utilization of GG based materials in food and petroleum industry. All the technical scientific issues have been addressed; highlighting the recent advancement.Entities:
Keywords: Drug & gene delivery; Food industry; Gellan gum; Oil recovery; Tissue engineering
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Year: 2017 PMID： 29157908 DOI： 10.1016/j.ijbiomac.2017.11.099
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953