| Literature DB >> 29156224 |
Dmitry V Yashunsky1, Alexander A Karelin1, Yury E Tsvetkov1, Nikolay E Nifantiev2.
Abstract
3-Aminopropyl β-(1 → 6)-d-glucotetraoside has been synthesized from 3-benzyloxycarbonylaminopropanol and 6-O-acetyl-2,3,4-tri-O-benzoyl-d-glucopyranosyl trichloroacetimidate by successive attachment of one monosaccharide unit in total yield of 22%. Free aminopropyl glycoside was converted into a biotin derivative that can be used for controlled immobilization of the oligosaccharide on streptavidin-coated ELISA plates and for tracing carbohydrate binding molecules.Entities:
Keywords: Biotin; Biotinylated oligosaccharides; Synthesis; β-(1 → 6)-d-glucan; β-(1 → 6)-d-oligoglucosides
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Year: 2017 PMID： 29156224 DOI： 10.1016/j.carres.2017.11.001
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104