Swarupa Kancherla1, Ahmara Ross1,2, Susan T Stefko1, Joseph N Martel1. 1. Eye and Ear Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and. 2. Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
Abstract
PURPOSE: This report describes a fulminant infection with Clostridium perfringens after an intravitreal anti-vascular endothelial growth factor injection. METHODS: This is a retrospective case review. RESULTS: Our patient's rapid infection eventually led to enucleation, despite broad-spectrum antibiotic therapy. CONCLUSION: Reporting rare causes and common clinical findings of C. perfringens ocular infection may lead to earlier detection and intervention.
PURPOSE: This report describes a fulminant infection with Clostridium perfringens after an intravitreal anti-vascular endothelial growth factor injection. METHODS: This is a retrospective case review. RESULTS: Our patient's rapid infection eventually led to enucleation, despite broad-spectrum antibiotic therapy. CONCLUSION: Reporting rare causes and common clinical findings of C. perfringensocular infection may lead to earlier detection and intervention.