Literature DB >> 29154411

Effect of graft size matching on pediatric living-donor liver transplantation at a single center.

Jun-Jie Li1, Cai-Hua Zu2, Shi-Peng Li3, Wei Gao1, Zhong-Yang Shen1, Jin-Zhen Cai1.   

Abstract

We retrospectively analyzed 252 patients with end-stage liver disease who had undergone LDLT from January 2009 to September 2015. Of these, 25 had a GRWR of <2.0% (Group A), 204 had a GRWR of ≥2.0% or <4.0% (Group B), and 23 had a GRWR ≥4.0% (Group C). The three GRWR groups demonstrated similar characteristics, except for recipient age and recipient BMI. The overall 1-, 2-, and 3-year graft survival rates were 95.1%, 93.5%, and 93.5%, respectively. However, among the three groups, graft survival rates at 1 year, 2 years, and 3 years were significantly different (P = .0009). Hepatic artery stenosis/thrombosis was more frequently observed in Group C than in Groups A and B (P = .001). Wound infection was also more frequently observed in Group C than in Group A and B (P = .002). However, intestinal fistula/bile leakage/biliary-enteric anastomotic fistula was more frequently observed in Group A than in Groups B and C (P = .001). In addition, reoperation more frequently occurred in Group A and C than in Group B (P = .001). Recipients with a GRWR between 2.0% and 4.0% had significantly better graft survival rates.
© 2017 The Authors. Clinical Transplantation Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  graft-to-recipient weight ratio; living-donor liver transplantation; patient and graft survival rates; pediatric

Mesh:

Year:  2017        PMID: 29154411     DOI: 10.1111/ctr.13160

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  3 in total

1.  Pediatric living donor liver transplantation (LDLT): Short- and long-term outcomes during sixteen years period at a single centre- A retrospective cohort study.

Authors:  Emad Hamdy Gad; Ahmed Nabil Sallam; Hosam Soliman; Tarek Ibrahim; Tahany Abdel Hameed Salem; Mohammed Abdel-Hafez Ali; Mohammed Al-Sayed Abd-Same; Islam Ayoub
Journal:  Ann Med Surg (Lond)       Date:  2022-06-07

Review 2.  Alternatives to left lateral sector in paediatric liver transplantation-a systematic review on monosegmental and reduced grafts.

Authors:  Paschalis Gavriilidis; Ernest Hidalgo
Journal:  Hepatobiliary Surg Nutr       Date:  2022-08       Impact factor: 8.265

3.  Adult liver transplantation using pediatric donor livers after cardiac or brain death: A report of three cases.

Authors:  Limin Ding; Lishan Deng; Xinchang Li; Zhidan Xu
Journal:  Exp Ther Med       Date:  2020-08-31       Impact factor: 2.447

  3 in total

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